13th World Congress for Laser Dentistry

26-28, April 2012

Barcelona, Spain

Meeting Abstract

Sponsors: World Federation for Laser Dentistry

-  Poster 104

TITLE: Use of Laser photobiomodulation in the evolution of oral mucositis associated with CMF chemotherapy protocol in patients with breast cancer-Case Report.

AUTHORS: Pires-Santos GM, Ferreira MFL, Oliveira SCPS, Monteiro JSC, Brugnera A, Pinheiro ALB.

Center of Biophotonics - School of Dentistry - Federal University of Bahia

SOURCE: Med Oral Patol Oral Cir Bucal. 2012 May 1;17(Supplement1):S252.

* doi:10.4317/medoral.17643752

http://dx.doi.org/10.4317/medoral.17643752

Abstract

The aim of this study was to evaluate the effectiveness of using a laser photobiomodulation on prevention and treatment of oral mucositis induced by chemotherapy protocol CMF (cyclophosphamide, methotrexate, 5-Fluouracil) in patients with breast cancer. Patients and Methods: We selected 12 patients who underwent 6 cycles of 21 days of treatment, with diagnosis of infiltrating ductal carcinoma (ICD C50.9). Were randomly divided into two groups: Group A with 6 patients (Protocol CMF + + Laser Protocol of stomatological CACON) Group B (Group C1 6 patients) were the control patients who received CMF hospital protocol established by CACON. The patients in Group A received the preventive use of FBML 24 hours before the start of chemotherapy cycle, then every 48 hours and was extended to one week after completion of chemotherapy. Results: In groups of oral mucositis grade 0 (64.29%), grade I (7.14%), grade II (14.29%), grade III (7.14%), grade IV (14.29 %) compared to group B, had mucositis grade 0 (35.71%), grade I (21.43%), grade II (28.57%), grade III (14.29%), grade IV (14.29%), patients who made use of FBML and as preventive therapy showed a reduction and pain relief in 42.86%. Conclusion: The low-power laser when used preventively or as therapeutic and showed immediate relief of pain and accelerate tissue repair.