Dutra SN, Pires FR, Armada L, Azevedo RS. Immunoexpression of Wnt/β-catenin signaling pathway proteins in ameloblastoma and calcifying cystic odontogenic tumor. J Clin Exp Dent. 2017;9(1):e136-40.

doi:10.4317/jced.53100

http://dx.doi.org/doi:10.4317/jced.53100

References

1. Chen J, Lan Y, Baek JA, Gao Y, Jiang R. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol. 2009;334:174-85. https://doi.org/10.1016/j.ydbio.2009.07.015 PMid:19631205 PMCid:PMC2752344

2. Sekine S, Sato S, Takata T, Fukuda Y, Ishida T, Kishino M, et al. Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas. Am J Pathol. 2003;163:1707-12. https://doi.org/10.1016/S0002-9440(10)63528-6 PMid:14578169

3. Wei Z, Zhong M, Guo Y, Wang Y, Ren M, Wang Z. Expression of β-catenin and AXIN2 in ameloblastomas. Contemp Oncol (Pozn). 2013;17:250-6. https://doi.org/10.5114/wo.2013.35278 PMid:24596510

4. Guimarães DM, Antunes DM, Saturno JL, Massuda F, Paiva KB, Nunes FD. Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts. Acta Histochem. 2015;117:667-74. https://doi.org/10.1016/j.acthis.2015.10.006 PMid:26558991

5. Hassanein AM, Glanz SM, Kessler HP, Eskin TA, Liu C. beta-Catenin is expressed aberrantly in tumors expressing shadow cells. Pilomatricoma, craniopharyngioma, and calcifying odontogenic cyst. Am J Clin Pathol. 2003;120:732-6. https://doi.org/10.1309/EALEG7LD6W7167PX PMid:14608900

6. Ahn SG, Kim SA, Kim SG, Lee SH, Kim J, Yoon JH. Beta-catenin gene alterations in a variety of so-called calcifying odontogenic cysts. APMIS. 2008;116:206-11. https://doi.org/10.1111/j.1600-0463.2008.00893.x PMid:18377586

7. Liu F, Millar SE. Wnt/beta-catenin signaling in oral tissue development and disease. J Dent Res. 2010;89:318-30. https://doi.org/10.1177/0022034510363373 PMid:20200414 PMCid:PMC3140915

8. Tanahashi J, Daa T, Yada N, Kashima K, Kondoh Y, Yokoyama S. Mutational analysis of Wnt signaling molecules in ameloblastoma with aberrant nuclear expression of beta-catenin. J Oral Pathol Med. 2008;37:565-70. https://doi.org/10.1111/j.1600-0714.2008.00645.x PMid:18284543

9. Lustig B, Behrens J. The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol. 2003;129:199-221. PMid:12707770

10. da Silva LP, Serpa MS, Tenório JR, do Nascimento GJ, de Souza-Andrade ES, Veras-Sobral AP. Retrospective study of 289 odontogenic tumors in a Brazilian population. Med Oral Patol Oral Cir Bucal. 2016;21:e271-5. https://doi.org/10.4317/medoral.21029 PMid:26827068 PMCid:PMC4867199

11. Mosqueda-Taylor A. New findings and controversies in odontogenic tumors. Med Oral Patol Oral Cir Bucal. 2008;13:E555-8. PMid:18758398

12. Filizzola AI, Bartholomeu-Dos-Santos TC, Pires FR. Ameloblastomas: Clinicopathological features from 70 cases diagnosed in a single Oral Pathology service in an 8-year period. Med Oral Patol Oral Cir Bucal. 2014;19:e556-61. https://doi.org/10.4317/medoral.19802 PMid:25129244 PMCid:PMC4259370

13. Utumi ER, Pedron IG, da Silva LP, Machado GG, Rocha AC. Different manifestations of calcifying cystic odontogenic tumor. Einstein (Sao Paulo). 2012;10:366-70. https://doi.org/10.1590/S1679-45082012000300019 PMid:23386019

14. Gomes da Silva W, Ribeiro Bartholomeu dos Santos TC, Cabral MG, Azevedo RS, Pires FR. Clinicopathologic analysis and syndecan-1 and Ki-67 expression in calcifying cystic odontogenic tumors, dentinogenic ghost cell tumor, and ghost cell odontogenic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117:626-33. https://doi.org/10.1016/j.oooo.2014.01.021 PMid:24534622

15. Ledesma-Montes C, Gorlin RJ, Shear M, Prae Torius F, Mosqueda-Taylor A, Altini M, et al. International collaborative study on ghost cell odontogenic tumours: calcifying cystic odontogenic tumour, dentinogenic ghost cell tumour and ghost cell odontogenic carcinoma. J Oral Pathol Med. 2008;37:302-8. https://doi.org/10.1111/j.1600-0714.2007.00623.x PMid:18221328

16. Siar CH, Nagatsuka H, Han PP, Buery RR, Tsujigiwa H, Nakano K, et al. Differential expression of canonical and non-canonical Wnt ligands in ameloblastoma. J Oral Pathol Med. 2012;41:332-9. https://doi.org/10.1111/j.1600-0714.2011.01104.x PMid:22077561

17. Clevers H. Wnt/beta-catenin signaling in development and disease. Cell. 2006;127: 469-80. https://doi.org/10.1016/j.cell.2006.10.018 PMid:17081971

18. Lin M, Li L, Liu C, Liu H, He F, Yan F, et al. Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth. Dev Dyn. 2011;240:432-40. https://doi.org/10.1002/dvdy.22550 PMid:21246660 PMCid:PMC3023990

19. Mikels AJ, Nusse R. Purified Wnt5a protein activates or inhibits beta-catenin–TCF signaling depending on receptor context. PLoS Biol. 2006;4:e115. https://doi.org/10.1371/journal.pbio.0040115 PMid:16602827 PMCid:PMC1420652

20. Nusse R, Varmus HE. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell. 1982;31:99-109. https://doi.org/10.1016/0092-8674(82)90409-3 PMid:6297757

21. Leocata P, Villari D, Fazzari C, Lentini M, Fortunato C, Nicotina PA. Syndecan-1 and Wingless-type protein-1 in human ameloblastomas. J Oral Pathol Med. 2007;36:394-9. https://doi.org/10.1111/j.1600-0714.2007.00537.x PMid:17617831

22. Kibe T, Fuchigami T, Kishida M, Iijima M, Ishihata K, Hijioka H, et al. A novel ameloblastoma cell line (AM-3) secretes MMP-9 in response to Wnt-3a and induces osteoclastogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:780-8. https://doi.org/10.1016/j.oooo.2013.03.005 PMid:23706918

23. Hakim SG, Kosmehl H, Sieg P, Trenkle T, Jacobsen HC, Attila Benedek G, et al. Altered expression of cell-cell adhesion molecules β-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors. Clin Oral Investig. 2011;15:321-8. https://doi.org/10.1007/s00784-010-0388-8 PMid:20195877

24. Sukarawan W, Simmons D, Suggs C, Long K, Wright JT. WNT5A expression in ameloblastoma and its roles in regulating enamel epithelium tumorigenic behaviors. Am J Pathol. 2010;176:461-71. https://doi.org/10.2353/ajpath.2010.090478 PMid:20008136 PMCid:PMC2797904

25. Rumayor A, Carlos R, Molina Kirsch H, de Andrade BA, Roma-ach MJ, de Almeida OP. Ghost cells in pilomatrixoma, craniopharyngioma, and calcifying cystic odontogenic tumor: histological, immunohistochemical, and ultrastructural study. J Oral Pathol Med. 2015;44:284-90. https://doi.org/10.1111/jop.12234 PMid:25047924

26. Tanaka A, Okamoto M, Yoshizawa D, Ito S, Alva PG, Ide F, et al. Presence of ghost cells and the Wnt signaling pathway in odontomas. J Oral Pathol Med. 2007;36:400-4. https://doi.org/10.1111/j.1600-0714.2007.00550.x PMid:17617832

27. Mehendiratta M, Bishen KA, Boaz K, Mathias Y. Ghost cells: A journey in the dark. Dent Res J (Isfahan). 2012;9:S1-8. PMid:23814549

28. Lo Muzio L. A possible role for the WNT-1 pathway in oral carcinogenesis. Crit Rev Oral Biol Med. 2001;12:152-65. https://doi.org/10.1177/10454411010120020501 PMid:11345525

29. Alves Pereira KM, do Amaral BA, dos Santos BR, Galvao HC, Freitas R de A, de Souza LB. Immunohistochemical expression of E-cadherin and beta-catenin in ameloblastomas and tooth germs. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:425-31. https://doi.org/10.1016/j.tripleo.2009.10.032 PMid:20219600

30. Miyake T, Tanaka Y, Kato K, Tanaka M, Sato Y, Ijiri R, et al. Gene mutation analysis and immunohistochemical study of beta-catenin in odontogenic tumors. Pathol Int. 2006;56:732-7. https://doi.org/10.1111/j.1440-1827.2006.02039.x PMid:17096730

31. Siriwardena BS, Kudo Y, Ogawa I, Tilakaratne WM, Takata T. Aberrant beta-catenin expression and adenomatous polyposis coli gene mutation in ameloblastoma and odontogenic carcinoma. Oral Oncol. 2009;45:103-8.
https://doi.org/10.1016/j.oraloncology.2008.03.008
PMid:18486530