Zeballos R, Bologna-Molina R, Pereira-Prado V, Villarroel-Dorrego M. Expression of parathyroid hormone related protein (PTHRP) in amelo­blastomas. J Clin Exp Dent. 2018;10(2):e172-6.

 

doi:10.4317/jced.54222

http://dx.doi.org/doi:10.4317/jced.54222

 

References

1. Carreón-Burciaga RG, González-González R, Molina-Frechero N, Bologna-Molina R. Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns. Dis Markers. 2015;2015:683087.
https://doi.org/10.1155/2015/683087
PMid:26823641 PMCid:PMC4707386

 

 

2. Bologna-Molina R, Mosqueda-Taylor A, Lopez-Corella E, Almeida OP, Carrasco-Daza D, Garcia-Vazquez F, et. al. Syndecan-1 (CD138) and Ki-67 expression in different subtypes of ameloblastomas. Oral Oncol. 2008;44:805-11.
https://doi.org/10.1016/j.oraloncology.2007.10.007
PMid:18207448

 

3. García-Muñoz A, Bologna-Molina R, A Rodríguez M, Liceága-Reyes R, Farfán-Morales JE, Aranda-Romo S, et al. Orosomucoid-1 Expression in Ameloblastoma Variants. Int J Mol Cell Med. 2016;5:49-56.

PMid:27386438 PMCid:PMC4916783

 

4. da Silva TA, Batista AC, Mendonça EF, Leles CR, Fukada S, Cunha FQ. Comparative expression of RANK, RANKL, and OPG in keratocystic odontogenic tumors, ameloblastomas, and dentigerous cysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:333-41.
https://doi.org/10.1016/j.tripleo.2007.06.009
PMid:18061491

 

5. González-González R, Molina-Frechero N, Damian-Matsumura P, Salazar-Rodriguez S, Bologna-Molina R. Immunohistochemical expression of Survivin and its relationship with cell apoptosis and proliferation in ameloblastomas. Dis Markers. 2015;2015:301781.
https://doi.org/10.1155/2015/301781
PMid:25866434 PMCid:PMC4381570

 

6. Qian Y, Huang HZ. The role of RANKL and MMP-9 in the bone resorption caused by ameloblastoma. J Oral Pathol Med. 2010;39:592-8.
https://doi.org/10.1111/j.1600-0714.2009.00882.x
PMid:20412401

 

7. Hendarmin L, Sandra F, Nakao Y, Ohishi M, Nakamura N. TNFalpha played a role in induction of Akt and MAPK signals in ameloblastoma. Oral Oncol. 2005;41:375-82.
https://doi.org/10.1016/j.oraloncology.2004.09.014
PMid:15792609

 

8. Fuchigami T, Kibe T, Koyama H, Kishida S, Iijima M, Nishizawa Y, et al. Regulation of IL-6 and IL-8 production by reciprocal cell-to-cell interactions between tumor cells and stromal fibroblasts through IL-1α in ameloblastoma. Biochem Biophys Res Commun. 2014;451:491-6.
https://doi.org/10.1016/j.bbrc.2014.07.137
PMid:25124663

 

9. Sathi GS, Nagatsuka H, Tamamura R, Fujii M, Gunduz M, Inoue M, et al. Stromal cells promote bone invasion by suppressing bone formation in ameloblastoma. Histopathology. 2008;53:458-67.
https://doi.org/10.1111/j.1365-2559.2008.03127.x
PMid:18983611

 

10. Gardella TJ, Jüppner H. Molecular properties of the PTH/PTHrP receptor. Trends Endocrinol Metab. 2001;12:210-7.
https://doi.org/10.1016/S1043-2760(01)00409-X

PMid:11397646

 

11. Gensure RC, Gardella TJ, Jüppner H. Parathyroid hormone and parathyroid hormone-related peptide, and their receptors. Biochem Biophys Res Commun. 2005;328:666-78.
https://doi.org/10.1016/j.bbrc.2004.11.069
PMid:15694400

 

12. Amizuka N, Davidson D, Liu H, Valverde-Franco G, Chai S, Maeda T, et. al. Signalling by fibroblast growth factor receptor 3 and parathyroid hormone-related peptide coordinate cartilage and bone development. Bone. 2004;34:13-25.
https://doi.org/10.1016/j.bone.2003.08.009
PMid:14751559

 

13. Wysolmerski JJ. Parathyroid hormone-related protein: an update. J Clin Endocrinol Metab. 2012;97:2947-56.
https://doi.org/10.1210/jc.2012-2142
PMid:22745236 PMCid:PMC3431578

 

14. Wise GE, Que BG, Huang H, Lumpkin SJ. Enhancement of gene expression in rat dental follicle cells by parathyroid hormone-related protein. Arch Oral Biol. 2000;45:903-9.
https://doi.org/10.1016/S0003-9969(00)00053-4

 

15. Yao S, Pan F, Wise GE. Chronological gene expression of parathyroid hormone-related protein (PTHrP) in the stellate reticulum of the rat: implications for tooth eruption. Arch Oral Biol. 2007;52:228-32.
https://doi.org/10.1016/j.archoralbio.2006.10.008
PMid:17116292

 

16. Ono W, Sakagami N, Nishimori S, Ono N, Kronenberg HM. Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation. Nat Commun. 2016;7:11277.
https://doi.org/10.1038/ncomms11277
PMid:27068606 PMCid:PMC4832076

 

17. Klingelhöffer C, Reck A, Ettl T, Morsczeck C. The parathyroid hormone-related protein is secreted during the osteogenic differentiation of human dental follicle cells and inhibits the alkaline phosphatase activity and the expression of DLX3. Tissue Cell. 2016;48:334-9.
https://doi.org/10.1016/j.tice.2016.05.007
PMid:27368119

 

18. Mak IW, Turcotte RE, Ghert M. Parathyroid hormone-related protein (PTHrP) modulates adhesion, migration and invasion in bone tumor cells. Bone. 2013;55:198-207.
https://doi.org/10.1016/j.bone.2013.02.020
PMid:23466453

 

19. Takagaki K, Takashima T, Onoda N, Tezuka K, Noda E, Kawajiri H, et. al. Parathyroid hormone-related protein expression, in combination with nodal status, predicts bone metastasis and prognosis of breast cancer patients. Exp Ther Med. 2012;3:963-968.
https://doi.org/10.3892/etm.2012.521
PMid:22970000 PMCid:PMC3438629

 

20. Shen X, Qian L, Falzon M. PTH-related protein enhances MCF-7 breast cancer cell adhesion, migration, and invasion via an intracrine pathway. Exp Cell Res. 2004;294:420-33.

PMid:15023531

 

21. Liu JG, Tabata MJ, Fujii T, Ohmori T, Abe M, Ohsaki Y, et al. Parathyroid hormone-related peptide is involved in protection against invasion of tooth germs by bone via promoting the differentiation of osteoclasts during tooth development. Mech Dev. 2000;95:189-200.
https://doi.org/10.1016/S0925-4773(00)00366-X

PMid:10906461

 

22. Mekaapiruk K, Suda N, Hammond VE, Beck F, Kuroda T, Takano Y, et. al. The influence of parathyroid hormone-related protein (PTHrP) on tooth-germ development and osteoclastogenesis in alveolar bone of PTHrP-knock out and wild-type mice in vitro. Arch Oral Biol. 2002;47:665-72.
https://doi.org/10.1016/S0003-9969(02)00026-2

PMid:12243970

 

23. Kitahara Y, Suda N, Kuroda T, Beck F, Hammond VE, Takano Y. Disturbed tooth development in parathyroid hormone-related protein (PTHrP)-gene knockout mice. Bone. 2002;30:48-56.
https://doi.org/10.1016/S8756-3282(01)00669-X

PMid:11792564

 

24. Abdelsayed RA, Vartanian RK, Smith KK, Ibrahim NA. Parathyroid hormone-related protein (PTHrP) expression in ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97:208-19.
https://doi.org/10.1016/j.tripleo.2003.10.003
PMid:14970780

 

25. Kurppa KJ, Catón J, Morgan PR, Ristimäki A, Ruhin B, Kellokoski J, et. al. High frequency of BRAF V600E mutations in ameloblastoma. J Pathol. 2014;232:492-498.
https://doi.org/10.1002/path.4317
PMid:24374844 PMCid:PMC4255689

 

26. Ohtsuru M. Expression of parathyroid hormone-related protein in ameloblastomas. Tokai J Exp Clin Med. 2005;30:233-9.
PMid:16482944

 

27. Kumamoto H, Ooya K. Expression of parathyroid hormone-related protein (PTHrP), osteoclast differentiation factor (ODF)/receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoclastogenesis inhibitory factor (OCIF)/osteoprotegerin (OPG) in ameloblastomas. J Oral Pathol Med. 2004;33:46-52.
https://doi.org/10.1111/j.1600-0714.2004.00204.x
PMid:14675140

 

28. Ota Y, Aoki T, Otsuru M, Hirabayashi K, Nakamura N, Tsukinoki K. Huge ameloblastoma associated with hypercalcemia, leukocytosis, and elevated tumor markers via production of parathyroid hormone-related protein and granulocyte colony-stimulating factor. J Oral Maxillofac Surg. 2012;70:1380-5.
https://doi.org/10.1016/j.joms.2011.06.003
PMid:21824706

 

29. Heikinheimo K, Kurppa KJ, Laiho A, Peltonen S, Berdal A, Bouattour A, et. al. Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor. J Dent Res. 2015;94:101-11.
https://doi.org/10.1177/0022034514556815
PMid:25398365

 

30. Ono W, Sakagami N, Nishimori S, Ono N, Kronenberg HM. Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation. Nat Commun. 2016;7:11277.
https://doi.org/10.1038/ncomms11277
PMid:27068606 PMCid:PMC4832076

 

31. Wise GE, Que BG, Huang H, Lumpkin SJ. Enhancement of gene expression in rat dental follicle cells by parathyroid hormone-related protein. Arch Oral Biol. 2000;45:903-9.
https://doi.org/10.1016/S0003-9969(00)00053-4

PMid:10973564

 

32. Boyle WJ1, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature. 2003;423:337-42.
https://doi.org/10.1038/nature01658
PMid:12748652