Vieira-Júnior JR, de Oliveira-Santos C, Della-Coletta R, Cristianismo-Costa D, Paranaíba LMR, Martelli-Júnior H. Immunoexpression of α2-integrin and Hsp47 in hereditary gingival fibromatosis and gingival fibromatosis-associated dental abnormalities. Med Oral Patol Oral Cir Bucal. 2013 Jan 1;18 (1):e45-8.

 

 

doi:10.4317/medoral.17970

http://dx.doi.org/doi:10.4317/medoral.17970

 

 

 

1. Takagi M, Yamamoto H, Mega H, Hsieh KJ, Shioda S, Enomoto S. Heterogeneity in the gingival fibromatoses. Cancer. 1991;68:2202-12.
http://dx.doi.org/10.1002/1097-0142(19911115)68:10<2202::AID-CNCR2820681019>3.0.CO;2-O

 

2. Dongari-Bagtzoglou A. Drug-associated gingival enlargement. J Periodontol. 2004;75:1424-31.
http://dx.doi.org/10.1902/jop.2004.75.10.1424
PMid:15562922

 

3. Coletta RD, Graner E. Hereditary gingival fibromatosis: A systematic review. J Periodontol. 2006;77:753-64.
http://dx.doi.org/10.1902/jop.2006.050379
PMid:16671866

 

4. Hakkinen L, Csiszar A. Hereditary gingival fibromatosis: characteristics and novel putative pathogenic mechanisms. J Dent Res. 2007;86:25-34.
http://dx.doi.org/10.1177/154405910708600104

 

5. Singer SL, Goldblatt J, Hallan LA, Winters JC. Hereditary gingival fibromatosis with a recessive mode of inheritance. Case reports. Aust Dent J. 1993;38:427-32.
http://dx.doi.org/10.1111/j.1834-7819.1993.tb04755.x
PMid:8110075

 

6. Martelli-Júnior H, Bonan PR, Dos Santos LA, Santos SM, Cavalcanti MG, Coletta RD. Case reports of a new syndrome associating gingival fibromatosis and dental abnormalities in a consanguineous family. J Periodontol. 2008;79:1287-96.
http://dx.doi.org/10.1902/jop.2008.070520
PMid:18597613

 

7. Ivarsson M, McWhirter A, Black CM, Rubin K. Impaired regulation of collagen pro-α1(I) mRNA and change in pattern of collagen-binding integrins on scleroderma fibroblasts. J Invest Dermatol. 1993;101:216-21.
http://dx.doi.org/10.1111/1523-1747.ep12364810
PMid:8345224

 

8. Langholz O, Rockel D, Mauch C, Kozlowska E, Bank I, Krieg T, et al. Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by α1β1 and α2β1 integrins. J Cell Biol. 1995;131:1903-15.
http://dx.doi.org/10.1083/jcb.131.6.1903
PMid:8557756

 

9. Riikonen T, Westermarck J, Koivisto L, Broberg A, Kahari VM, Heino J. Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression. J Biol Chem. 1995;270:13548-52.
PMid:7768957

 

10. Fujimura T, Moriwaki S, Imokawa G, Takema Y. Crucial role of fibroblasts integrins alpha2 and beta1 in maintaining the structural and mechanical properties of the skin. J Dermatol Sci. 2007;45:45-53.
http://dx.doi.org/10.1016/j.jdermsci.2006.09.012
PMid:17118629

 

11. Nagata K. Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum. Matrix Biol. 1998;16:379-86.
http://dx.doi.org/10.1016/S0945-053X(98)90011-7

 

12. Bozzo L, Almeida OP, Scully C, Aldred MJ. Hereditary gingival fibromatosis. Report of an extensive four-generation pedigree. Oral Surg Oral Med Oral Pathol. 1994;78:452-4.
http://dx.doi.org/10.1016/0030-4220(94)90037-X

 

13. Martelli-Júnior H, Lemos DP, Silva CO, Graner E, Coletta RD. Hereditary gingival fibromatosis: report of a five-generation family using cellular proliferation analysis. J Periodontol. 2005;76:2299-305.
http://dx.doi.org/10.1902/jop.2005.76.12.2299
PMid:16332243

 

14. Vigneswaran N, Zhao W, Dassanayake A, Muller S, Miller DM, Zacharias W. Variable expression of cathepsin B and D correlates with highly invasive and metastatic phenotype of oral cancer. Hum Pathol. 2000;31:931-7.
http://dx.doi.org/10.1053/hupa.2000.9035
PMid:10987253

 

15. Zhou J, Meng LY, Ye XQ, Von der Hoff JW, Bian Z. Increased expression of integrin alpha 2 and abnormal response to TGF-β1 in hereditary gingival fibromatosis. Oral Dis. 2009;15:414-21.
http://dx.doi.org/10.1111/j.1601-0825.2009.01567.x
PMid:19422573

 

16. Nagata K, Hosokawa N. Regulation and function of collagen-specific molecular chaperone, HSP47. Cell Struct Funct. 1996;21:425-30.
http://dx.doi.org/10.1247/csf.21.425

 

17. Bolcato-Bellemin A-L, Elkaim R, Tenenbaum H. Expression of RNAs encoding for α and β integrin subunits in periodontitis and in cyclosporin A gingival overgrowth. J Clin Periodontol. 2003;30:937-43.
http://dx.doi.org/10.1034/j.1600-051X.2003.00402.x
PMid:14761114

 

18. Kataoka M, Seto H, Wada C, Kido J, Nagata T. Decreased expression of α2 integrin in fibroblasts isolated from cyclosporin A-induced gingival overgrowth in rats. J Periodontal Res. 2003;38:533-7.
http://dx.doi.org/10.1034/j.1600-0765.2003.00692.x
PMid:12941079

 

19. Slambrouk SV, Jenkins AR, Romero AE, Steelant WFA. Reorganization of the integrin α2 subunit controls cell adhesion and cancer cell invasion in prostate cancer. Int J Oncol. 2009;34:1717-26.

 

20. O'Sullivan J, Bitu CC, Daly SB, Urquhart JE, Barron MJ, Bhaskar SS, et al. Whole-exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfect and gingival hyperplasia syndrome. Am J Hum Genet. 2011;88:616-20.
http://dx.doi.org/10.1016/j.ajhg.2011.04.005
PMid:21549343 PMCid:3146735

 

21. Martelli-Júnior H, Santos CO, Bonan PR, Moura PF, Bitu CC, León JE, et al. Minichromosome maintenance 2 and 5 expression is increased in the epithelium of hereditary gingival fibromatosis associated with dental abnormalities. Clinics. 2011;66:753-7.
http://dx.doi.org/10.1590/S1807-59322011000500008
PMid:21789376 PMCid:3109371

 

22. Shiuan-Shinn L, Ling-Hsien T, Yi-Ching L, Chung-Hung T, Yu-Chao C. Heat shock protein 47 in oral squamous cell carcinomas and upregulated by arecoline in human oral ephitelial cells. J Oral Pathol Med. 2011;40:390-6.
http://dx.doi.org/10.1111/j.1600-0714.2010.00998.x
PMid:21198874

 

23. Tagushi T, Nazneen A, Al-Shihri AA, Turkistani KA, Razzaque MS. Heat shock protein 47: A novel biomarker of phenotypically altered collagen-producing cells. Acta Histochem Cytochem. 2011;44:35-41.
http://dx.doi.org/10.1267/ahc.11001
PMid:21614164 PMCid:3096080

 

24. Totan S, Echo A, Yuksel E. Heat shock proteins modulate keloid formation. Eplasty. 2011;11:190-202.