Benevenuto-de-Andrade BA, León JE, Carlos R, Delgado-Azañero W, Mosqueda-Taylor A, Paes-de-Almeida O. Immunohistochemical expression of Skp2 protein in oral nevi and melanoma. Med Oral Patol Oral Cir Bucal. 2013 May 1;18 (3):e388-91.  

 

doi:10.4317/medoral.18781

http://dx.doi.org/doi:10.4317/medoral.18781

 

1. Li W, Sanki A, Karim RZ, Thompson JF, Soon Lee C, Zhuang L, et al. The role of cell cycle regulatory proteins in the pathogenesis of melanoma. Pathology. 2006;38:287-301.
http://dx.doi.org/10.1080/00313020600817951
PMid:16916716

 

2. Penin RM, Fernandez-Figueras MT, Puig L, Rex J, Ferrandiz C, Ariza A. Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation. Mod Pathol. 2002;15:1227-35.
http://dx.doi.org/10.1097/01.MP.0000036589.99516.D6
PMid:12429803

 

3. Li Q, Murphy M, Ross J, Sheehan C, Carlson JA. Skp2 and p27kip1 expression in melanocytic nevi and melanoma: an inverse relationship. J Cutan Pathol. 2004;31:633-42.
http://dx.doi.org/10.1111/j.0303-6987.2004.00243.x
PMid:15491322

 

4. Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol. 1999;1:193-9.
http://dx.doi.org/10.1038/12013
PMid:10559916

 

5. Sutterlüty H, Chatelain E, Marti A, Wirbelauer C, Senften M, Müller U, et al. p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. Nat Cell Biol. 1999;1:207-14.
http://dx.doi.org/10.1038/12027
PMid:10559918

 

6. Lim MS, Adamson A, Lin Z, Perez-Ordonez B, Jordan RC, Tripp S, et al. Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: correlation with p27(Kip1) and proliferation index. Blood. 2002;100:2950-6.
http://dx.doi.org/10.1182/blood.V100.8.2950
PMid:12351407

 

7. Kudo Y, Kitajima S, Sato S, Miyauchi M, Ogawa I, Takata T. High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas. Cancer Res. 2001;61:7044-7.
PMid:11585732

 

8. Oliveira AM, Okuno SH, Nascimento AG, Lloyd RV. Skp2 protein expression in soft tissue sarcomas. J Clin Oncol. 2003;21:722-7.
http://dx.doi.org/10.1200/JCO.2003.05.112
PMid:12586812

 

9. Woenckhaus C, Maile S, Uffmann S, Bansemir M, Dittberner T, Poetsch M, et al. Expression of Skp2 and p27KIP1 in naevi and malignant melanoma of the skin and its relation to clinical outcome. Histol Histopathol. 2005;20:501-8.
PMid:15736055

 

10. Prasad ML, Patel SG, Huvos AG, Shah JP, Busam KJ. Primary mucosal melanoma of the head and neck: a proposal for microstaging localized, Stage I (lymph node-negative) tumors. Cancer. 2004;100:1657-64.
http://dx.doi.org/10.1002/cncr.20201
PMid:15073854

 

11. Rose AE, Wang G, Hanniford D, Monni S, Tu T, Shapiro RL, et al. Clinical relevance of SKP2 alterations in metastatic melanoma. Pigment Cell Melanoma Res. 2011;24:197-206.
http://dx.doi.org/10.1111/j.1755-148X.2010.00784.x
PMid:20883453 PMCid:3341662

 

12. Chen G, Cheng Y, Zhang Z, Martinka M, Li G. Cytoplasmic Skp2 expression is increased in human melanoma and correlated with patient survival. PLoS One. 2011;6:e17578.
http://dx.doi.org/10.1371/journal.pone.0017578
PMid:21386910 PMCid:3046256

 

13. Alonso SR, Ortiz P, Pollán M, Pérez-Gómez B, Sánchez L, Acu-a MJ, et al. Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study. Am J Pathol. 2004;164:193-203.
http://dx.doi.org/10.1016/S0002-9440(10)63110-0

 

14. Ben-Izhak O, Lahav-Baratz S, Meretyk S, Ben-Eliezer S, Sabo E, Dirnfeld M, et al. Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer. J Urol. 2003;170:241-5.
http://dx.doi.org/10.1097/01.ju.0000072113.34524.a7
PMid:12796697

 

15. Gstaiger M, Jordan R, Lim M, Catzavelos C, Mestan J, Slingerland J, et al. Skp2 is oncogenic and overexpressed in human cancers. Proc Natl Acad Sci U S A. 2001;98:5043-8.
http://dx.doi.org/10.1073/pnas.081474898
PMid:11309491 PMCid:33160

 

16. Hershko D, Bornstein G, Ben-Izhak O, Carrano A, Pagano M, Krausz MM, et al. Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. Cancer. 2001;91:1745-51.
http://dx.doi.org/10.1002/1097-0142(20010501)91:9<1745::AID-CNCR1193>3.0.CO;2-H

 

17. Shim EH, Johnson L, Noh HL, Kim YJ, Sun H, Zeiss C, et al. Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate. Cancer Res. 2003;63:1583-8.
PMid:12670908