Soares CD, Hernandez-Guerrero JC, Andrade BABd, Romañach MJ, Mosqueda-Taylor A, Carlos R, et al. Comparative expression of cyclooxygenase 2 and Ki67 in amelanotic and conventional oral melanomas. Med Oral Patol Oral Cir Bucal. 2020 Nov 1;25 (6):e728-31.


doi:10.4317/medoral.23737

https://dx.doi.org/doi:10.4317/medoral.23737


1. Lourenço SV, Fernandes JD, Hsieh R, Coutinho-Camillo CM, Bologna S, Sangueza M, et al. Head and neck mucosal melanoma: A review. Am J Dermatopathol. 2014;36:578-87.

https://doi.org/10.1097/DAD.0000000000000035

PMid:24423929 

2. Moshe M, Levi A, Ad-El D, Ben-Amitai D, Mimouni D, Didkovsky E, et al. Malignant melanoma clinically mimicking pyogenic granuloma: comparison of clinical evaluation and histopathology. Melanoma Res. 2018;28:363-7.

https://doi.org/10.1097/CMR.0000000000000451

PMid:29750750 

3. Cheung WL, Patel RR, Leonard A, Firoz B, Meehan SA. Amelanotic melanoma: a detailed morphologic analysis with clinicopathologic correlation of 75 cases. J Cutan Pathol. 2012;39:33-9.

https://doi.org/10.1111/j.1600-0560.2011.01808.x

PMid:22050235 

4. Fitzpatrick F. Cyclooxygenase Enzymes: Regulation and Function. Curr Pharm Des. 2005;10:577-88.

https://doi.org/10.2174/1381612043453144

PMid:14965321 

5. Hashemi Goradel N, Najafi M, Salehi E, Farhood B, Mortezaee K. Cyclooxygenase-2 in cancer: A review. J Cell Physiol. 2019;234:5683-99.

https://doi.org/10.1002/jcp.27411

PMid:30341914 

6. Xia M, Duan ML, Tong JH, Xu JG. MiR-26b suppresses tumor cell proliferation, migration and invasion by directly targeting COX-2 in lung cancer. Eur Rev Med Pharmacol Sci. 2015;19:4728-37.

PMid:26744864

7. Hu H, Han T, Zhuo M, Wu LL, Yuan C, Wu L, et al. Elevated COX-2 Expression Promotes Angiogenesis Through EGFR/p38-MAPK/Sp1-Dependent Signalling in Pancreatic Cancer. Sci Rep. 2017;7:470.

https://doi.org/10.1038/s41598-017-00288-4

PMid:28352075 PMCid:PMC5428057

8. Guo Z, Jiang JH, Zhang J, Yang HJ, Yang FQ, Qi YP, et al. COX-2 Promotes Migration and Invasion by the Side Population of Cancer Stem Cell-Like Hepatocellular Carcinoma Cells. Medicine (Baltimore). 2015;94:e1806.

https://doi.org/10.1097/MD.0000000000001806

PMid:26554780 PMCid:PMC4915881

9. Semaan J, Pinon A, Rioux B, Hassan L, Limami Y, Pouget C, et al. Resistance to 3-HTMC-Induced Apoptosis Through Activation of PI3K/Akt, MEK/ERK, and p38/COX-2/PGE2 Pathways in Human HT-29 and HCT116 Colorectal Cancer Cells. J Cell Biochem. 2016;117:2875-85.

https://doi.org/10.1002/jcb.25600

PMid:27192488 

10. Montezuma MAP, Fonseca FP, Benites BM, Soares CD, do Amaral-Silva GK, de Almeida OP, et al. COX-2 as a determinant of lower disease-free survival for patients affected by ameloblastoma. Pathol Res Pract. 2018;214:907-13.

https://doi.org/10.1016/j.prp.2018.03.014

PMid:29559247 

11. Soares CD, Borges CF, Sena-Filho M, Almeida OP, Stelini RF, Cintra ML, et al. Prognostic significance of cyclooxygenase 2 and phosphorylated Akt1 overexpression in primary nonmetastatic and metastatic cutaneous melanomas. Melanoma Res. 2017;27:448-56.

https://doi.org/10.1097/CMR.0000000000000368

PMid:28604419 

12. Prasad ML, Patel SG, Huvos AG, Shah JP, Busam KJ. Primary mucosal melanoma of the head and neck: a proposal for microstaging localized, Stage I (lymph node-negative) tumors. Cancer. 2004;100:1657-64.

https://doi.org/10.1002/cncr.20201

PMid:15073854 

13. Soares C, Melo de Lima Morais T, Carlos R, Mariano FV, Altemani A, Freire de Carvalho MG, et al. Phosphorylated Akt1 expression is associated with poor prognosis in cutaneous, oral and sinonasal melanomas. Oncotarget. 2018;9:37291-304.

https://doi.org/10.18632/oncotarget.26458

PMid:30647870 PMCid:PMC6324666

14. Soliman NA, Yussif SM. Ki-67 as a prognostic marker according to breast cancer molecular subtype. Cancer Biol Med. 2016;13:496-504.

https://doi.org/10.20892/j.issn.2095-3941.2016.0066

PMid:28154782 PMCid:PMC5250608

15. Ma X, Wu Y, Zhang T, Song H, Jv H, Guo W, et al. Ki67 proliferation index as a histopathological predictive and prognostic parameter of oral mucosal melanoma in patients without distant metastases. J Cancer. 2017;8:3828-37.

https://doi.org/10.7150/jca.20935

PMid:29151970 PMCid:PMC5688936