Azab NA, Zahran FM, Amin AAW, Rady NH. DNA integrity in diagnosis of premalignant lesions. Med Oral Patol Oral Cir Bucal. 2021 Jul 1;26 (4):e445-50.

 

doi:10.4317/medoral.24287

https://dx.doi.org/doi:10.4317/medoral.24287


1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394-424.

https://doi.org/10.3322/caac.21492

PMid:30207593 

2. Jin LJ, Lamster IB, Greenspan JS, Pitts NB, Scully C, Warnakulasuriya S. Global burden of oral diseases: emerging concepts, management and interplay with systemic health. Oral Dis. 2016;22:609-19.

https://doi.org/10.1111/odi.12428

PMid:26704694 

3. Lingen MW, Abt E, Agrawal N, Chaturvedi AK, Cohen E, D'Souza G, et al. Evidence-based clinical practice guideline for the evaluation of potentially malignant disorders in the oral cavity: A report of the American Dental Association. J Am Dent Assoc. 2017;48:712-27.

https://doi.org/10.1016/j.adaj.2017.07.032

PMid:28958308 

4. Raj AT, Kheur S, Gupta AA, Patil VR, Kharat A. The need for combination immunotherapy in oncology. Oral Oncol. 2019;91:123.

https://doi.org/10.1016/j.oraloncology.2019.02.013

PMid:30786965 

5. Dionne K, Warnakulasuriya S, Zain R, Cheong S. Potentially malignant disorders of the oral cavity: Current practice and future directions in the clinic and laboratory. Int J Cancer. 2015;136:503-15.

https://doi.org/10.1002/ijc.28754

PMid:24482244 

6. Stuani VT, Rubira CMF, Sant'Ana ACP, Santos PSS. Salivary biomarkers as tools for oral squamous cell carcinoma diagnosis: A systematic review. Head Neck. 2017;39:797-811.

https://doi.org/10.1002/hed.24650

PMid:27898189 

7. Kustanovich A, Schwartz R, Peretz T, Grinshpun A. Life and death of circulating cell-free DNA. Cancer Biol Ther. 2019;20:1057-67.

https://doi.org/10.1080/15384047.2019.1598759

PMid:30990132 PMCid:PMC6606043

8. Krishnamurthy N, Spencer E, Torkamani A, Nicholson L. Liquid Biopsies for Cancer: Coming to a Patient near You. J Clin Med. 2017;6:3.

https://doi.org/10.3390/jcm6010003

PMid:28054963 PMCid:PMC5294956

9. Peng M, Chen C, Hulbert A, Brock MV, Yu F. Non-blood circulating tumor DNA detection in cancer. Oncotarget. 2017;8:69162.

https://doi.org/10.18632/oncotarget.19942

PMid:28978187 PMCid:PMC5620327

10. Stötzer OJ, Lehner J, Fersching-Gierlich D, Nagel D, Holdenrieder S. Diagnostic relevance of plasma DNA and DNA integrity for breast cancer. Tumor Biol. 2014;35:1183-91.

https://doi.org/10.1007/s13277-013-1158-4

PMid:24018822 

11. Solari-Twadell PA. Recreational drugs. Societal and professional issues. Nurs Clin North Am. 1991;26:499-509.

PMid:2047294

12. Williams PM, Poh CF, Hovan AJ, Ng S, Rosin MP. Evaluation of a suspicious oral mucosal lesion. J Can Dent Assoc (Tor). 2008;74 :275-80.

PMid:18387268

13. Kumar SV, Hurteau GJ, Spivack SD. Validity of messenger RNA expression analyses of human saliva. Clin Cancer Res. 2006;12:5033-9.

https://doi.org/10.1158/1078-0432.CCR-06-0501

PMid:16951218 

14. Longo MC, Berninger MS, Hartley JL. Use of uracil DNA glycosylase to control carry-over contamination in polymerase chain reactions. Gene. 1990;93:125-8.

https://doi.org/10.1016/0378-1119(90)90145-H

PMid:2227421

15. Arko-Boham B, Aryee NA, Blay RM, Owusu EDA, Tagoe EA, Doris Shackie ES, et al. Circulating cell-free DNA integrity as a diagnostic and prognostic marker for breast and prostate cancers. Cancer Genet. 2019;235:65-71.

https://doi.org/10.1016/j.cancergen.2019.04.062

PMid:31105051 

16. Jiang W, Zahurak M, Goldenberg D, Milman Y, Park HL, Westra WH, et al. Increased plasma DNA integrity index in head and neck cancer patients. Int J cancer. 2006;119:2673-6.

https://doi.org/10.1002/ijc.22250

PMid:16991120 

17. Roopashree MR, Gondhalekar R V, Shashikanth MC, George J, Thippeswamy SH, Shukla A. Pathogenesis of oral lichen planus--a review. J oral Pathol Med. 2010;39:729-34.

https://doi.org/10.1111/j.1600-0714.2010.00946.x

PMid:20923445 

18. Kamel, Teama S, Fawzy A, El Deftar M, Kamel AM, Teama S, et al. Plasma DNA integrity index as a potential molecular diagnostic marker for breast cancer. Tumor Biol. 2016;37:7565-72.

https://doi.org/10.1007/s13277-015-4624-3

PMid:26684805 

19. Desai A, Kallianpur S, Mani A, Tijare MS, Khan S, Jain M, et al. Quantification of circulating plasma cell free DNA fragments in patients with oral cancer and precancer. Gulf J Oncolog. 2018;1:11.

PMid:30145546

20. Sriram KB, Relan V, Clarke BE, Duhig EE, Windsor MN, Matar KS, et al. Pleural fluid cell-free DNA integrity index to identify cytologically negative malignant pleural effusions including mesotheliomas. BMC Cancer. 2012;12:428.

https://doi.org/10.1186/1471-2407-12-428

PMid:23009708 PMCid:PMC3495778

21. Bronkhorst AJ, Ungerer V, Holdenrieder S. The emerging role of cell-free DNA as a molecular marker for cancer management. Biomol Detect Quantif. 2019;17:100087.

https://doi.org/10.1016/j.bdq.2019.100087

PMid:30923679 PMCid:PMC6425120

22. Pu D, Liang H, Wei F, Akin D, Feng Z, Yan QX, et al. Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study. Thorac Cancer. 2016;7:428-36.

https://doi.org/10.1111/1759-7714.12350

PMid:27385985 PMCid:PMC4930962

23. Markopoulos AK, Michailidou EZ, Tzimagiorgis G. Salivary Markers for Oral Cancer Detection. Open Dent J. 2010;4:172.

https://doi.org/10.2174/1874210601004010172

PMid:21673842 PMCid:PMC3111739

24. Baňasová L, Kamodyová N, Janšáková K, Tóthová Ľ, Stanko P, Turňa J, et al. Salivary DNA and markers of oxidative stress in patients with chronic periodontitis. Clin Oral Investig. 2015;19:201-7.

https://doi.org/10.1007/s00784-014-1236-z

PMid:24677171 

25. Gorgannezhad L, Umer M, Islam MN, Nguyen NT, Shiddiky MJA. Circulating tumor DNA and liquid biopsy: Opportunities, challenges, and recent advances in detection technologies. Lab Chip. 2018;18:1174-96.

https://doi.org/10.1039/C8LC00100F

PMid:29569666 

26. Eltorgoman AE, Badr EAE, Kombr YFAE, Yousif M. Pleural fluid DNA integrity index as a diagnostic marker of malignant pleural effusion. Br J Biomed Sci. 2017;74:148-51.

https://doi.org/10.1080/09674845.2017.1297215

PMid:28537492 

27. Cheng, Tang Q, Cao X, Burwinkel B, Cheng J, Tang Q, et al. Cell-free circulating DNA Integrity based on peripheral blood as a biomarker for diagnosis of cancer: a systematic review. Cancer Epidemiol Biomarkers Prev. 2017;26:1595-602.

https://doi.org/10.1158/1055-9965.EPI-17-0502

PMid:28830871