Yanaguizawa WH, Barros FB, Kobayashi-Velasco S, Salineiro FC, Alves FA, Cavalcanti MG. Computed tomography bone density variations in oncological patients undergoing antiresorptive medication. Med Oral Patol Oral Cir Bucal. 2022 Nov 1;27 (6):e489-96.



doi:10.4317/medoral.25191

https://dx.doi.org/doi:10.4317/medoral.25191


1. Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw-2014 Update. J Oral Maxillofac Surg. 2014;72:1938-56.

https://doi.org/10.1016/j.joms.2014.04.031

PMid:25234529 

2. Vassiliou V, Tselis N, Kardamakis D. Osteonecrosis of the jaws: Clinicopathologic and radiologic characteristics, preventive and therapeutic strategies. Strahlentherapie und Onkol. 2010;186:367-73.

https://doi.org/10.1007/s00066-010-2066-9

PMid:20437019 

3. Baba A, Ojiri H, Goto TK, Ikeda K,Yamauchi H, Ogino N, et al. Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (4), CT and MR imaging findings of antiresorptive agent-related osteonecrosis of the jaws/medication-related osteonecrosis of the jaw (secondary publication). Jpn Dent Sci Rev. 2019;55:58-64.

https://doi.org/10.1016/j.jdsr.2018.11.001

PMid:30815046 PMCid:PMC6378898

4. Annemiksad R, Lai K-C, Dodson TB, Woo S-B, Treister NS, Akinyemi O, et al. Quality of Life Implications of Bisphosphonate-Associated Osteonecrosis of the Jaw. Oncologist. 2011;16:121-32.

https://doi.org/10.1634/theoncologist.2010-0183

PMid:21212433 PMCid:PMC3228058

5. Dal Prá KJ, Lemos CAA, Okamoto R, Soubhia AMP, Pellizzer EP. Efficacy of the C-terminal telopeptide test in predicting the development of bisphosphonate-related osteonecrosis of the jaw: a systematic review. Int J Oral Maxillofac Surg. 2017;46:151-6.

https://doi.org/10.1016/j.ijom.2016.10.009

PMid:27876532 

6. Soares MQS, Van Dessel J, Jacobs R, Santos PSS, Cestari TM, Garlet GP, et al. Zoledronic Acid Induces Site-Specific Structural Changes and Decreases Vascular Area in the Alveolar Bone. J Oral Maxillofac Surg. 2018;76:1893-1901.

https://doi.org/10.1016/j.joms.2018.03.007

PMid:29626448 

7. Hamada H, Matsuo A, Koizumi T, Satomi T, Chikazu D. A simple evaluation method for early detection of bisphosphonate-related osteonecrosis of the mandible using computed tomography. J Cranio-Maxillofacial Surg. 2014;42:924-9.

https://doi.org/10.1016/j.jcms.2014.01.012

PMid:24503386 

8. Taniguchi T, Ariji Y, Nozawa M, Naitoh M, Kuroiwa Y, Kurita K, et al. Computed tomographic assessment of early changes of the mandible in bisphosphonate-treated patients. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122:362-72.

https://doi.org/10.1016/j.oooo.2016.06.002

PMid:27544397 

9. Aljohani S, Fliefel R, Ihbe J, Kühnisch J, Ehrenfeld M, Otto S. What is the effect of anti-resorptive drugs (ARDs) on the development of medication-related osteonecrosis of the jaw (MRONJ) in osteoporosis patients: A systematic review. J Craniomaxillofac Surg. 2017;45:1493-502.

https://doi.org/10.1016/j.jcms.2017.05.028

PMid:28687467 

10. Duarte NT, Rech B de O, Martins IG, Franco JB, Ortega KL. Can children be affected by bisphosphonate-related osteonecrosis of the jaw? A systematic review. Int J Oral Maxillofac Surg. 2020;49:183-91.

https://doi.org/10.1016/j.ijom.2019.08.004

PMid:31447218 

11. De Oliveira MM, Malta DC, Guauche H, de Moura L, Azevedo e Silva G. Estimativa de pessoas com diagnóstico de câncer no Brasil: Dados da pesquisa nacional de saúde, 2013. Rev Bras Epidemiol. 2015;18:146-57.

https://doi.org/10.1590/1980-5497201500060013

PMid:27008610 

12. Migliorati CA, Casiglia J, Epstein J, Jacobsem PL, Siegel MA, Woo SB. Managing the care of patients with bisphosphonate-associated osteonecrosis: An American Academy of Oral Medicine position paper. J Am Dent Assoc. 2005;136:1658-68.

https://doi.org/10.14219/jada.archive.2005.0108

PMid:16383047 

13. Khan AA, Morrison A, Kendler DL, Rizzoli R, Hanley DA, Felsenberg D, et al. Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ. J Clin Densitom. 2017;20:8-24.

https://doi.org/10.1016/j.jocd.2016.09.005

PMid:27956123 

14. Pittman K, Antill YC, Goldrick A, Goh J, de Boer RH. Denosumab: Prevention and management of hypocalcemia, osteonecrosis of the jaw and atypical fractures. Asia Pac J Clin Oncol. 2017;13:266-76.

https://doi.org/10.1111/ajco.12517

PMid:27862983 

15. Franchi S, Brucoli M, Boffano P, Dosio C, Benech A. Medical students' knowledge of medication related osteonecrosis of the jaw. J Stomatol Oral Maxillofac Surg. 2020;121:344-6.

PMid:31672685

16. Vassiliou V, Tselis N, Kardamakis D. Osteonecrosis of the Jaws. Strahlentherapie und Onkol. 2010;186:367-73.

https://doi.org/10.1007/s00066-010-2066-9

PMid:20437019 

17. El-Rabbany M, Sgro A, Lam DK, Shah PS, Azarpazhooh A. Effectiveness of treatments for medication-related osteonecrosis of the jaw. J Am Dent Assoc. 2017;148:584-94.e2.

https://doi.org/10.1016/j.adaj.2017.04.002

PMid:28527518 

18. Lopes RN, Rabelo GD, Rocha AC, Carvalho PAG, Alves FA. Surgical Therapy for Bisphosphonate-Related Osteonecrosis of the Jaw: Six-Year Experience of a Single Institution. J Oral Maxillofac Surg. 2015;73:1288-95.

https://doi.org/10.1016/j.joms.2015.01.008

PMid:25871903 

19. Kün-Darbois JD, Libouban H, Mabilleau G, Pascaretti-Grizon F, Chappard D. Bone mineralization and vascularization in bisphosphonate-related osteonecrosis of the jaw: an experimental study in the rat. Clin Oral Investig. 2018;22:2997-3006.

https://doi.org/10.1007/s00784-018-2385-2

PMid:29453497 

20. Martelli SJR, Damian MF, Schinestsck AR, Schuch LF, Cascaes AM, Vasconcelos ACU. Imaging and histomorphometric evaluation of mandible and tibia of rats treated with bisphosphonates. Oral Maxillofac Surg. 2019;23:473-9.

https://doi.org/10.1007/s10006-019-00807-9

PMid:31686251 

21. Jain V, Seith A, Manchanda S, Pillai R, Sharma D, Mathur V. Effect of intravenous administration of zoledronic acid on jaw bone density in cases having skeletal metastasis: A prospective clinical study. J Indian Prosthodont Soc. 2019;19:203.

https://doi.org/10.4103/jips.jips_368_18

PMid:31462858 PMCid:PMC6685335

22. Silva IM de CC, Freitas DQ, Ambrosano GMB, Bóscolo FN, Almeida SM. Bone density : comparative evaluation of Hounsfield units in multislice and cone-beam computed tomography. Braz Oral Res. 2012;26:550-6.

https://doi.org/10.1590/S1806-83242012000600011

PMid:23184166 

23. Schreiber JJ, Anderson PA, Rosas HG, Buchholz AL, Au AG. Hounsfield Units for Assessing Bone Mineral Density and Strength: A Tool for Osteoporosis Management. J Bone Jt Surgery-American Vol. 2011;93:1057-63.

https://doi.org/10.2106/JBJS.J.00160

PMid:21655899 

24. Heim N, Götz W, Kramer F, Faron A. Antiresorptive drug-related changes of the mandibular bone densitiy in medication-related osteonecrosis of the jaw patients. Dentomaxillofacial Radiol. 2019;48:20190132.

https://doi.org/10.1259/dmfr.20190132

PMid:31530019 PMCid:PMC6951096

25. Goller-Bulut D, Ozcan G, Avci F. Changes in dimension of neurovascular canals in the mandible and maxilla: A radiographic finding in patients diagnosed with MRONJ. Med Oral Patol Oral y Cir Bucal. 2018;23:282-9.

https://doi.org/10.4317/medoral.22274

PMid:29680848 PMCid:PMC5945243

26. Torres SR, Chen CSK, Leroux BG, Lee PP, Hollender LG, Santos ECA, et al. Mandibular cortical bone evaluation on cone beam computed tomography images of patients with bisphosphonate-related osteonecrosis of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113:695-703.

https://doi.org/10.1016/j.oooo.2011.11.011

PMid:22668629 

27. Koo C-H, Lee J-H. Evaluation of mandibular cortical bone ratio on computed tomography images in patients taking bisphosphonates. Maxillofac Plast Reconstr Surg. 2018;40:17.

https://doi.org/10.1186/s40902-018-0153-5

PMid:30038904 PMCid:PMC6031557

28. Bransford R, Goergens E, Briody J, Amanat N, Cree A, Little D. Effect of zoledronic acid in an L6-L7 rabbit spine fusion model. Eur Spine J. 2007;16:557-62.

https://doi.org/10.1007/s00586-006-0212-y

PMid:16967298 PMCid:PMC2229826

29. Quattrocchi CC, Santini D, Dell'Aia P, Piciucchi S, Leoncini E, Vincenziet B, al. A prospective analysis of CT density measurements of bone metastases after treatment with zoledronic acid. Skeletal Radiol. 2007;36:1121-7.

https://doi.org/10.1007/s00256-007-0388-1

PMid:17912514