Lázaro-Abdulkarim A, Hernández-Alfaro F, Puigdollers-Pérez A, Giralt-Hernando M, Elnayef B, Valls-Ontañón A. Is efficacy of miniscrew-assisted rapid palatal expansion in mid to late adolescents and young adults related to craniofacial sutures opening? A systematic review and meta-analysis. Med Oral Patol Oral Cir Bucal. 2025 Mar 1;30 (2):e271-81.


doi:10.4317/medoral.26935

https://dx.doi.org/doi:10.4317/medoral.26935


1. Brunetto DP, Sant'Anna EF, Machado AW, Moon W. Non-surgical treatment of transverse deficiency in adults using microimplant-assisted rapid palatal expansion (MARPE). Dental Press J Orthod. 2017;22:110-25.

https://doi.org/10.1590/2177-6709.22.1.110-125.sar

PMid:28444019 PMCid:PMC5398849

2. Storto CJ, Garcez AS, Suzuki H, Cusmanich KG, Elkenawy I, Moon W, et al. Assessment of respiratory muscle strength and airflow before and after microimplant-assisted rapid palatal expansion. Angle Orthod. 2019;89:713-20.

https://doi.org/10.2319/070518-504.1

PMid:30896250 PMCid:PMC8111838

3. Park JJ, Park YC, Lee KJ, Cha JY, Tahk JH, Choi YJ. Skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion in young adults: A cone-beam computed tomography study. Korean J Orthod. 2017;47:77-86.

https://doi.org/10.4041/kjod.2017.47.2.77

PMid:28337417 PMCid:PMC5359634

4. Seong EH, Choi SH, Kim HS, Yu HS, Park YC, Lee KJ. Evaluation of the effects of miniscrew incorporation in palatal expanders for young adults using finite element analysis. Korean J Orthod. 2018;48:81-9.

https://doi.org/10.4041/kjod.2018.48.2.81

PMid:29564217 PMCid:PMC5854885

5. Garib DG, Castanha Henriques JF, Janson G, Freitas MR, Coelho RA. Rapid maxillary expansion--tooth tissue-borne versus tooth-borne expanders: a computed tomography evaluation of dentoskeletal effects. Angle Orthod. 2005;75:548-57.

PMid:16097223

6. Shin H, Hwang CJ, Lee KJ, Choi YJ, Han SS, Yu HS. Predictors of midpalatal suture expansion by miniscrew-assisted rapid palatal expansion in young adults: A preliminary study. Korean J Orthod. 2019;49:360-71.

https://doi.org/10.4041/kjod.2019.49.6.360

PMid:31815104 PMCid:PMC6883215

7. Moon W, Wu KW, MacGinnis M, Sung J, Chu H, Youssef G, et al. The efficacy of maxillary protraction protocols with the micro-implant-assisted rapid palatal expander (MARPE) and the novel N2 mini-implant-a finite element study. Prog Orthod. 2015;16:16.

https://doi.org/10.1186/s40510-015-0083-z

PMid:26061987 PMCid:PMC4456601

8. Suzuki H, Moon W, Previdente LH, Suzuki SS, Silva Garcez A, Consolaro A. Miniscrew-assisted rapid palatal expander (MARPE): the quest for pure orthopedic movement. Dent Press J Orthod. 2016;21:17-23.

https://doi.org/10.1590/2177-6709.21.4.017-023.oin

PMid:27653260 PMCid:PMC5029312

9. Persson M, Thilander B. Palatal suture closure in man from 15 to 35 years of age. Am J Orthod. 1977;72:42-52.

https://doi.org/10.1016/0002-9416(77)90123-3

PMid:267435 

10. Silva-Montero JC, Faus-Matoses I, Ribas-Pérez D, Pourhamid H, Solano-Medonza B. Analysis of the frequency and correlated factors of midpalatal suture maturation stages in young adults, based on cone beam computed tomography imaging. J Clin Med. 2022;11:6959.

https://doi.org/10.3390/jcm11236959

PMid:36498534 PMCid:PMC9740603

11. Willershausen I, Erbe C, Al-Maawi S, Orlowska A, Wehrbein H, Ghanaati S. Development of a novel histological and histomorphometric evaluation protocol for a standardized description of the mid-palatal suture - An ex vivo study. J Anat. 2019;235:180-8.

https://doi.org/10.1111/joa.12985

PMid:30945289 PMCid:PMC6580068

12. Celenk-Koca T, Erdinc AE, Hazar S, Harris L, English JD, Akyalcin S. Evaluation of miniscrew-supported rapid maxillary expansion in adolescents: A prospective randomized clinical trial. Angle Orthod. 2018;88:702-9.

https://doi.org/10.2319/011518-42.1

PMid:30102085 PMCid:PMC8174075

13. Steinhauser EW. Midline splitting of the maxilla for correction of malocclusion. J Oral Surg. 1972;30:413-22.

PMid:4555048

14. Choi SH, Shi KK, Cha JY, Park YC, Lee KJ. Nonsurgical miniscrew-Assisted rapid maxillary expansion results in acceptable stability in young adults. Angle Orthod. 2016;86:713-20.

https://doi.org/10.2319/101415-689.1

PMid:26938955 PMCid:PMC8600851

15. Hernández-Alfaro F, Bueno JM, Diaz A, Pagés CM. Minimally invasive surgically assisted rapid palatal expansion with limited approach under sedation: A report of 283 consecutive cases. J Oral Maxillofac Surg. 2010;68:2154-8.

https://doi.org/10.1016/j.joms.2009.09.080

PMid:20584567 

16. Pulver RJ, Campbell PM, Opperman LA, Buschang PH. Miniscrew-assisted slow expansion of mature rabbit sutures. Am J Orthod Dentofac Orthop. 2016;150:303-12.

https://doi.org/10.1016/j.ajodo.2015.12.026

PMid:27476364 

17. Lee KJ, Park YC, Park JY, Hwang WS. Miniscrew-assisted nonsurgical palatal expansion before orthognathic surgery for a patient with severe mandibular prognathism. Am J Orthod Dentofac Orthop. 2010;137:830-9.

https://doi.org/10.1016/j.ajodo.2007.10.065

PMid:20685540 

18. MacGinnis M, Chu H, Youssef G, Wu KW, Machado AW, Moon W. The effects of micro-implant assisted rapid palatal expansion (MARPE) on the nasomaxillary complex--a finite element method (FEM) analysis. Prog Orthod. 2014;15:52.

https://doi.org/10.1186/s40510-014-0052-y

PMid:25242527 PMCid:PMC4148550

19. Winsauer H, Walter A, Scherfler M, Ploder O. What are the limits of microimplant-assisted palatal expanders?. Am J Orthod Dentofac Orthop. 2017;151:3-4.

https://doi.org/10.1016/j.ajodo.2016.09.011

PMid:28024780 

20. Cantarella D, Dominguez-Mompell R, Mallya SM, Moschik C, Pan HC, Miller J, et al. Changes in the midpalatal and pterygopalatine sutures induced by micro-implant-supported skeletal expander, analyzed with a novel 3D method based on CBCT imaging. Prog Orthod. 2017;18:34.

https://doi.org/10.1186/s40510-017-0188-7

PMid:29090368 PMCid:PMC5663987

21. Kim SY, Park YC, Lee KJ, Lintermann A, Han SS, Yu HS, et al. Assessment of changes in the nasal airway after nonsurgical miniscrew-assisted rapid maxillary expansion in young adults. Angle Orthod. 2018;88:435-41.

https://doi.org/10.2319/092917-656.1

PMid:29561652 PMCid:PMC8191933

22. Yoon S, Lee DY, Jung SK. Influence of changing various parameters in miniscrew-assisted rapid palatal expansion: A three-dimensional finite element analysis. Korean J Orthod. 2019;49:150-60.

https://doi.org/10.4041/kjod.2019.49.3.150

PMid:31149605 PMCid:PMC6533180

23. Lim HM, Park YC, Lee KJ, Kim KH, Choi YJ. Stability of dental, alveolar, and skeletal changes after miniscrew-assisted rapid palatal expansion. Korean J Orthod. 2017;47:313-22.

https://doi.org/10.4041/kjod.2017.47.5.313

PMid:28861393 PMCid:PMC5548712

24. Haas OL, Becker OE, De Oliveira RB. Computer-aided planning in orthognathic surgery - Systematic review. Int J Oral Maxillofac Surg. 2015;44:329-42.

https://doi.org/10.1016/j.ijom.2014.10.025

PMid:25432508 

25. Lin L, Ahn HW, Kim SJ, Moon SC, Kim SH, Nelson G. Tooth-borne vs bone-borne rapid maxillary expanders in late adolescence. Angle Orthod. 2015;85:253-62.

https://doi.org/10.2319/030514-156.1

PMid:25490552 PMCid:PMC8631879

26. Li N, Sun W, Li Q, Dong W, Martin D, Guo J. Skeletal effects of monocortical and bicortical mini-implant anchorage on maxillary expansion using cone-beam computed tomography in young adults. Am J Orthod Dentofac Orthop. 2020;157:651-61.

https://doi.org/10.1016/j.ajodo.2019.05.021

PMid:32354438 

27. Annarumma F, Posadino M, De Mari A, Drago S, Aghazada H, Gravina GM, et al. Skeletal and dental changes after maxillary expansion with a bone-borne appliance in young and late adolescent patients. Am J Orthod Dentofac Orthop. 2021;159:e363-75.

https://doi.org/10.1016/j.ajodo.2020.11.031

PMid:33573898 

28. Yi F, Liu S, Lei L, Liu O, Zhang L, Peng Q, et al. Changes of the upper airway and bone in microimplant-assisted rapid palatal expansion: A cone-beam computed tomography (CBCT) study. J Xray Sci Technol. 2020;28:271-83.

https://doi.org/10.3233/XST-190597

PMid:31985485 

29. Elkenawy I, Fijany L, Colak O, Paredes NA, Gargoum A, Abedini S, et al. An assessment of the magnitude, parallelism, and asymmetry of micro-implant-assisted rapid maxillary expansion in non-growing patients. Prog Orthod. 2020;21:42.

https://doi.org/10.1186/s40510-020-00342-4

PMid:33225406 PMCid:PMC7680816

30. Cho AR, Park JH, Moon W, Chae JM, Kang KH. Short-term effects of microimplant-assisted rapid palatal expansion on the circummaxillary sutures in skeletally mature patients: A cone-beam computed tomography study. Am J Orthod Dentofac Orthop. 2022;161:e187-97.

https://doi.org/10.1016/j.ajodo.2021.01.023

PMid:34872829 

31. Tang H, Liu P, Liu X, Hou Y, Chen W, Zhang L, et al. Skeletal width changes after mini-implant-assisted rapid maxillary expansion (MARME) in young adults. Angle Orthod. 2021;91:301-6.

https://doi.org/10.2319/052920-491.1

PMid:33492395 PMCid:PMC8084465

32. Jesus AS, Oliveira CB, Murata WH, Gonçales ES, Pereira-Filho VA, Santos-Pinto A. Nasomaxillary effects of miniscrew-assisted rapid palatal expansion and two surgically assisted rapid palatal expansion approaches. Int J Oral Maxillofac Surg. 2021;50:1059-68.

https://doi.org/10.1016/j.ijom.2020.12.014

PMid:33478814 

33. de Oliveira CB, Ayub P, Ledra IM, Murata WH, Suzuki SS, Ravelli DB, et al. Microimplant assisted rapid palatal expansion vs surgically assisted rapid palatal expansion for maxillary transverse discrepancy treatment. Am J Orthod Dentofac Orthop. 2021;159:733-42.

https://doi.org/10.1016/j.ajodo.2020.03.024

PMid:33931257 

34. Li Q, Tang H, Liu X, Luo Q, Jiang Z, Martin D, et al. Comparison of dimensions and volume of upper airway before and after mini-implant assisted rapid maxillary expansion. Angle Orthod. 2020;90:432-41.

https://doi.org/10.2319/080919-522.1

PMid:33378437 PMCid:PMC8032299

35. Winsauer H, Walter A, Ploder O. Success and Complication Rate of Miniscrew Assisted Non-Surgical Palatal Expansion In Adults-A Consecutive Study Using A Novel Force-Controlled Polycyclic Activation Protocol. Head Face Med. 2021;17:50.

https://doi.org/10.1186/s13005-021-00301-2

PMid:34895287 PMCid:PMC8665552

36. Colak O, Paredes NA, Elkenawy I, Torres M, Bui J, Jahangiri S, et al. Tomographic assessment of palatal suture opening pattern and pterygopalatine suture disarticulation in the axial plane after midfacial skeletal expansion. Prog Orthod. 2020;21:21.

https://doi.org/10.1186/s40510-020-00321-9

PMid:32686018 PMCid:PMC7370251

37. Chun JH, de Castro ACR, Oh S, Kim KH, Choi SH, Nojima LI, et al. Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT. BMC Oral Health. 2022;22:1-14.

https://doi.org/10.1186/s12903-022-02138-w

PMid:35395801 PMCid:PMC8994336

38. Lee DW, Park JH, Moon W, Seo HY, Chae JM. Effects of bicortical anchorage on pterygopalatine suture opening with microimplant-assisted maxillary skeletal expansion. Am J Orthod Dentofac Orthop. 2021;159:502-11.

https://doi.org/10.1016/j.ajodo.2020.02.013

PMid:33495061 

39. McMullen C, Al Turkestani NN, Ruellas ACO, Massaro C, Rego MVNN, Yatabe MS, et al. Three-dimensional evaluation of skeletal and dental effects of treatment with maxillary skeletal expansion. Am J Orthod Dentofac Orthop. 2022;161:666-78.

https://doi.org/10.1016/j.ajodo.2020.12.026

PMid:34980520 PMCid:PMC9050833

40. Grünheid T, Larson CE, Larson BE. Midpalatal suture density ratio: A novel predictor of skeletal response to rapid maxillary expansion. Am J Orthod Dentofac Orthop. 2017;151:267-76.

https://doi.org/10.1016/j.ajodo.2016.06.043

PMid:28153155