Serna-García M, Formaggio A, Carceller MC, Romero JJ, Flacco N. Identification of actin cytoskeleton organization genes in oral cancer and oral potentially malignant disorders using oral tissue RNA-seq database. Med Oral Patol Oral Cir Bucal. 2025 Nov 1;30 (6):e857-65.
doi:10.4317/medoral.27364
https://dx.doi.org/doi:10.4317/medoral.27364
1. Pollard TD, Cooper JA. Actin, a central player in cell shape and movement. Science. 2009;326:1208-12. |
PMid:19965462 PMCid:PMC3677050 |
2. Ivanov AI, Hunt D, Utech M, Nusrat A, Parkos CA. Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex. Mol Biol Cell. 2005;16:2636-50. |
PMid:15800060 PMCid:PMC1142412 |
3. Lamouille S, Xu J, Derynck R.Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2014;15:178. |
PMid:24556840 PMCid:PMC4240281 |
4. Yamaguchi H, Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta. 2007;1773:642. |
PMid:16926057 PMCid:PMC4266238 |
5. Aseervatham J. Cytoskeletal Remodeling in Cancer. Biology (Basel). 2020;9:1-40. |
PMid:33171868 PMCid:PMC7695181 |
6. Zhou S, Zhu Y, Li Z, Zhu Y, He Z, Zhang C. Exosome-derived long non-coding RNA ADAMTS9-AS2 suppresses progression of oral submucous fibrosis via AKT signalling pathway. J Cell Mol Med. 2021;25:2262-73. |
PMid:33345447 PMCid:PMC7882956 |
7. Tuch BB, Laborde RR, Xu X, Gu J, Chung CB, Monighetti CK, et al. Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations. PLoS One. 2010;5:e9317. |
PMid:20174472 PMCid:PMC2824832 |
8. Xu S, Song Y, Shao Y, Zhou H. Comprehensive analysis of circular RNA in oral leukoplakia: upregulated circHLA-C as a potential biomarker for diagnosis and prognosis. Ann Transl Med. 2020;8:1375-75. |
PMid:33313120 PMCid:PMC7723659 |
9. Law CW, Alhamdoosh M, Su S, Smyth GK, Ritchie ME. RNA-seq analysis is easy as 1-2-3 with limma, Glimma and edgeR. F1000Res. 2016;5:1408. |
PMid:27441086. PMCid:PMC4937821 |
10. Hoo ZH, Candlish J, Teare D. What is an ROC curve? Emerg Med J. 2017;34:357-9. |
PMid:28302644 |
11. Khan K, Gogonea V, Fox PL. Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis. Transl Oncol. 2022;19:101392. |
PMid:35278792 PMCid:PMC8914993 |
12. Kim S, You S, Hwang D. Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping. Nat Rev Cancer. 2011;11:708-18. |
PMid:21941282 |
13. Son SS, Jeong HS, Lee SW, Lee ES, Lee JG, Lee JH, et al. EPRS1-mediated fibroblast activation and mitochondrial dysfunction promote kidney fibrosis. Exp Mol Med. 2024;56:2673-89. |
PMid:39623092 PMCid:PMC11671583 |
14. Lin LQ, Lv SY, Ren HZ, Li RR, Li L, Pang YQ, et al. Evodiamine inhibits EPRS expression to regulate glutamate metabolism and proliferation of oral squamous cell carcinoma cells. Kaohsiung J Med Sci. 2024;40:348-59. |
PMid:38243370 PMCid:PMC11895605 |
15. Kovac B, Mäkela TP, Vallenius T. Increased α-actinin-1 destabilizes E-cadherin-based adhesions and associates with poor prognosis in basal-like breast cancer. PLoS One. 2018;13:e0196986. |
PMid:29742177 PMCid:PMC5942811 |
16. Xie GF, Zhao LD, Chen Q, Tang DX, Chen QY, Lu HF, et al. High ACTN1 Is Associated with Poor Prognosis, and ACTN1 Silencing Suppresses Cell Proliferation and Metastasis in Oral Squamous Cell Carcinoma. Drug Des Devel Ther. 2020;14:1717-27. |
PMid:32440097 PMCid:PMC7211328 |
17. Villalonga E, Mosrin C, Normand T, Girardin C, Serrano A, Žunar B, et al. LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features. Cells. 2023;12:805. |
PMid:36899941 PMCid:PMC10000741 |
18. Lagoutte E, Villeneuve C, Lafanechère L, Wells CM, Jones GE, Chavrier P, et al. LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP. Sci Rep. 2016;6:24925. |
PMid:27116935 PMCid:PMC4847008 |
19. Shi B, Ma C, Liu G, Guo Y. MiR-106a directly targets LIMK1 to inhibit proliferation and EMT of oral carcinoma cells. Cell Mol Biol Lett. 2019;24:1. |
PMid:30873211 PMCid:PMC6402160 |
20. Kase-Kato I, Asai S, Minemura C, Tsuneizumi K, Oshima S, Koma A, et al. Molecular pathogenesis of the coronin family: Coro2a facilitates migration and invasion abilities in oral squamous cell carcinoma. Int J Mol Sci. 2021;22:12684. |
PMid:34884487 PMCid:PMC8657730 |
21. Ong MS, Deng S, Halim CE, Cai W, Tan TZ, Huang RYJ, et al. Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective. Cancers (Basel). 2020;12:238. |
PMid:31963677 PMCid:PMC7017214 |
22. Heuser VD, Mansuri N, Mogg J, Kurki S, Repo H, Kronqvist P, et al. Formin Proteins FHOD1 and INF2 in Triple-Negative Breast Cancer: Association With Basal Markers and Functional Activities. Breast Cancer (Auckl). 2018;12:1178223418792247. |
PMid:30158824 PMCid:PMC6109849 |
23. Masoudi M, Seki M, Yazdanparast R, Yachie N, Aburatani H. A genome-scale CRISPR/Cas9 knockout screening reveals SH3D21 as a sensitizer for gemcitabine. Sci Rep. 2019;9:19188. |
PMid:31844142 PMCid:PMC6915784 |
24. Wang W, Eddy R, Condeelis J. The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer. 2007;7:429-40. |
PMid:17522712 PMCid:PMC4270061 |
25. Nishimura S, Tsuda H, Kataoka F, Arao T, Nomura H, Chiyoda T, et al. Overexpression of cofilin 1 can predict progression-free survival in patients with epithelial ovarian cancer receiving standard therapy. Hum Pathol. 2011;42:516-21. |
PMid:21237490 |
26. Turhani D, Krapfenbauer K, Thurnher D, Langen H, Fountoulakis M. Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis. Electrophoresis. 2006;27:1417-23. |
PMid:16568407 |
27. Zhang N, Gao Y, Bian Q, Wang Q, Shi Y, Zhao Z, et al. The role of fascin-1 in the pathogenesis, diagnosis and management of respiratory related cancers. Front Oncol. 2022;12:948110. |
PMid:36033434 PMCid:PMC9404296 |
28. Liu H, Hao W, Wang X, Zhang Y, He L, Xue X, et al. Identification of novel molecules and pathways associated with fascin actin bundling protein 1 in laryngeal squamous cell carcinoma through comprehensive transcriptome analysis. Int J Mol Med. 2024;53:39. |
PMid:38426543 PMCid:PMC10914310 |
29. Lii CK, Chang JW, Chen JJ, Chen HW, Liu KL, Yeh SL, et al. Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways. Oncotarget. 2016;7:25162-79. |
PMid:27036017 PMCid:PMC5041895 |
30. Hopkins AM, Walsh SV, Verkade P, Boquet P, Nusrat A. Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. J Cell Sci. 2003;116:725-42. |
PMid:12538773 |
31. Sun Z, Guo X, Chen H, Ling J, Zhao H, Chang A, et al. MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma. Mol Carcinog. 2023;62:920-39. |
PMid:37014156 |
32. Chai AWY, Tan YH, Ooi S, Yee PS, Yee SM, Cheong SC. TNO155 is a selective SHP2 inhibitor to target PTPN11-dependent oral squamous cell carcinoma. Heliyon. 2024;10:e39677. |
PMid:39524880 PMCid:PMC11550046 |
33. Li B, Chen X, Xian H, Wen Q, Wang T. Gene mutation analysis of oral submucous fibrosis cancerization in Hainan Island. PeerJ. 2023;11:e16392. |
PMid:38050610 PMCid:PMC10693820 |
34. Zhao Y, Feng X, Zhao Y, Yang H, Zhang C. Overexpression of ST7-AS1 enhances apoptosis and inhibits proliferation of papillary thyroid carcinoma cells via microRNA-181b-5p-dependent inhibition of Tripartite Motif Containing 3. Mol Biotechnol. 2023;65:477-90. |
PMid:36030355 |
35. Zhuang L, Wang X, Wang Z, Ma X, Han B, Zou H, et al. MicroRNA-23b functions as an oncogene and activates AKT/GSK3β/β-catenin signaling by targeting ST7L in hepatocellular carcinoma. Cell Death Dis. 2017;8:e2804. |
PMid:28518144 PMCid:PMC5520730 |
36. Katoh M. Molecular cloning and characterization of ST7R (ST7-like, ST7L) on human chromosome 1p13, a novel gene homologous to tumor suppressor gene ST7 on human chromosome 7q31. Int J Oncol. 2002;20:1247-53. |
PMid:12012006 |