ÿþ<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=Content-Type content="text/html; charset=unicode"> <meta name=ProgId content=Word.Document> <meta name=Generator content="Microsoft Word 15"> <meta name=Originator content="Microsoft Word 15"> <link rel=File-List href="27549_1.fld/filelist.xml"> <link rel=Edit-Time-Data href="27549_1.fld/editdata.mso"> <!--[if !mso]> <style> v\:* {behavior:url(#default#VML);} o\:* {behavior:url(#default#VML);} w\:* {behavior:url(#default#VML);} .shape {behavior:url(#default#VML);} </style> <![endif]--><!--[if gte mso 9]><xml> <o:DocumentProperties> <o:Author>Jose.V.Bagan@uv.es</o:Author> <o:LastAuthor>Jose.V.Bagan@uv.es</o:LastAuthor> <o:Revision>2</o:Revision> <o:TotalTime>93</o:TotalTime> <o:Created>2025-12-14T16:21:00Z</o:Created> <o:LastSaved>2025-12-14T16:21:00Z</o:LastSaved> <o:Pages>1</o:Pages> <o:Words>2458</o:Words> <o:Characters>13522</o:Characters> <o:Lines>112</o:Lines> <o:Paragraphs>31</o:Paragraphs> <o:CharactersWithSpaces>15949</o:CharactersWithSpaces> <o:Version>16.00</o:Version> </o:DocumentProperties> <o:OfficeDocumentSettings> <o:AllowPNG/> </o:OfficeDocumentSettings> </xml><![endif]--> <link rel=themeData href="27549_1.fld/themedata.thmx"> <link rel=colorSchemeMapping href="27549_1.fld/colorschememapping.xml"> <!--[if gte mso 9]><xml> <w:WordDocument> <w:Zoom>184</w:Zoom> <w:SpellingState>Clean</w:SpellingState> <w:TrackMoves>false</w:TrackMoves> <w:TrackFormatting/> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning/> <w:ValidateAgainstSchemas/> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF/> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables/> <w:SnapToGridInCell/> <w:WrapTextWithPunct/> <w:UseAsianBreakRules/> <w:DontGrowAutofit/> <w:SplitPgBreakAndParaMark/> <w:EnableOpenTypeKerning/> <w:DontFlipMirrorIndents/> <w:OverrideTableStyleHps/> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math"/> <m:brkBin m:val="before"/> <m:brkBinSub m:val="&#45;-"/> <m:smallFrac m:val="off"/> <m:dispDef/> <m:lMargin m:val="0"/> <m:rMargin m:val="0"/> <m:defJc m:val="centerGroup"/> <m:wrapIndent m:val="1440"/> <m:intLim m:val="subSup"/> <m:naryLim m:val="undOvr"/> </m:mathPr></w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" DefUnhideWhenUsed="false" DefSemiHidden="false" DefQFormat="false" DefPriority="99" LatentStyleCount="376"> <w:LsdException Locked="false" Priority="0" QFormat="true" Name="Normal"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 1"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 2"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 3"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 4"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 5"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 6"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 7"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 8"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 9"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 7"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 8"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 9"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 1"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 2"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 3"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 4"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 5"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 6"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 7"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 8"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 9"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal Indent"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footnote text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="header"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footer"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index heading"/> <w:LsdException Locked="false" Priority="35" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="caption"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="table of figures"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="envelope address"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="envelope return"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footnote reference"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation reference"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="line number"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="page number"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="endnote reference"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="endnote text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="table of authorities"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="macro"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="toa heading"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 5"/> <w:LsdException Locked="false" Priority="10" QFormat="true" Name="Title"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Closing"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Signature"/> <w:LsdException Locked="false" Priority="1" SemiHidden="true" UnhideWhenUsed="true" Name="Default Paragraph Font"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Message Header"/> <w:LsdException Locked="false" Priority="11" QFormat="true" Name="Subtitle"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Salutation"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Date"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text First Indent"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text First Indent 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Note Heading"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Block Text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Hyperlink"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="FollowedHyperlink"/> <w:LsdException Locked="false" Priority="22" QFormat="true" Name="Strong"/> <w:LsdException Locked="false" Priority="20" QFormat="true" Name="Emphasis"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Document Map"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Plain Text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="E-mail Signature"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Top of Form"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Bottom of Form"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal (Web)"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Acronym"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Address"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Cite"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Code"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Definition"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Keyboard"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Preformatted"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Sample"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Typewriter"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Variable"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal Table"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation subject"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="No List"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 7"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 8"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 7"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 8"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Contemporary"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Elegant"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Professional"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Subtle 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Subtle 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Balloon Text"/> <w:LsdException Locked="false" Priority="39" Name="Table Grid"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Theme"/> <w:LsdException Locked="false" SemiHidden="true" Name="Placeholder Text"/> <w:LsdException Locked="false" Priority="1" QFormat="true" Name="No Spacing"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading"/> <w:LsdException Locked="false" Priority="61" Name="Light List"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3"/> <w:LsdException Locked="false" Priority="70" Name="Dark List"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 1"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 1"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 1"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 1"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 1"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 1"/> <w:LsdException Locked="false" SemiHidden="true" Name="Revision"/> <w:LsdException Locked="false" Priority="34" QFormat="true" Name="List Paragraph"/> <w:LsdException Locked="false" Priority="29" QFormat="true" Name="Quote"/> <w:LsdException Locked="false" Priority="30" QFormat="true" Name="Intense Quote"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 1"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 1"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 1"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 1"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 1"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 1"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 1"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 1"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 2"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 2"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 2"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 2"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 2"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 2"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 2"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 2"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 2"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 2"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 2"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 2"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 2"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 2"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 3"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 3"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 3"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 3"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 3"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 3"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 3"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 3"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 3"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 3"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 3"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 3"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 3"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 3"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 4"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 4"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 4"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 4"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 4"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 4"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 4"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 4"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 4"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 4"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 4"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 4"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 4"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 4"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 5"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 5"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 5"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 5"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 5"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 5"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 5"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 5"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 5"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 5"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 5"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 5"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 5"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 5"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 6"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 6"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 6"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 6"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 6"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 6"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 6"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 6"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 6"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 6"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 6"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 6"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 6"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 6"/> <w:LsdException Locked="false" Priority="19" QFormat="true" Name="Subtle Emphasis"/> <w:LsdException Locked="false" Priority="21" QFormat="true" Name="Intense Emphasis"/> <w:LsdException Locked="false" Priority="31" QFormat="true" Name="Subtle Reference"/> <w:LsdException Locked="false" Priority="32" QFormat="true" Name="Intense Reference"/> <w:LsdException Locked="false" Priority="33" QFormat="true" Name="Book Title"/> <w:LsdException Locked="false" Priority="37" SemiHidden="true" UnhideWhenUsed="true" Name="Bibliography"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="TOC Heading"/> <w:LsdException Locked="false" Priority="41" Name="Plain Table 1"/> <w:LsdException Locked="false" Priority="42" Name="Plain Table 2"/> <w:LsdException Locked="false" Priority="43" Name="Plain Table 3"/> <w:LsdException Locked="false" Priority="44" Name="Plain Table 4"/> <w:LsdException Locked="false" Priority="45" Name="Plain Table 5"/> <w:LsdException Locked="false" Priority="40" Name="Grid Table Light"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 1"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 1"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 1"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 1"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 1"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 2"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 2"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 2"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 2"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 2"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 3"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 3"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 3"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 3"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 3"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 4"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 4"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 4"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 4"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 4"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 5"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 5"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 5"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 5"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 5"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 6"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 6"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 6"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 6"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 6"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 6"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 6"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 1"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 1"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 1"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 1"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 1"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 2"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 2"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 2"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 2"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 2"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 3"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 3"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 3"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 3"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 3"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 4"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 4"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 4"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 4"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 4"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 5"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 5"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 5"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 5"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 5"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 6"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 6"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 6"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 6"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 6"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 6"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Mention"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Smart Hyperlink"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Hashtag"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Unresolved Mention"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Smart Link"/> </w:LatentStyles> </xml><![endif]--> <style> <!-- /* Font Definitions */ @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536870145 1107305727 0 0 415 0;} @font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-536859905 -1073732485 9 0 511 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-font-kerning:1.0pt; mso-ligatures:standardcontextual; mso-fareast-language:EN-US;} a:link, span.MsoHyperlink {mso-style-priority:99; color:blue; text-decoration:underline; text-underline:single;} a:visited, span.MsoHyperlinkFollowed {mso-style-noshow:yes; mso-style-priority:99; color:#954F72; mso-themecolor:followedhyperlink; text-decoration:underline; text-underline:single;} p {mso-style-noshow:yes; mso-style-priority:99; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";} p.MsoNoSpacing, li.MsoNoSpacing, div.MsoNoSpacing {mso-style-noshow:yes; mso-style-priority:1; mso-style-unhide:no; mso-style-qformat:yes; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";} p.msonormal0, li.msonormal0, div.msonormal0 {mso-style-name:msonormal; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";} span.SpellE {mso-style-name:""; mso-spl-e:yes;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-font-kerning:0pt; mso-ligatures:none; mso-fareast-language:EN-US;} @page WordSection1 {size:595.0pt 842.0pt; margin:70.85pt 3.0cm 70.85pt 3.0cm; mso-header-margin:35.4pt; mso-footer-margin:35.4pt; mso-paper-source:0;} div.WordSection1 {page:WordSection1;} --> </style> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-fareast-language:EN-US;} </style> <![endif]--><!--[if gte mso 9]><xml> <o:shapedefaults v:ext="edit" spidmax="1026"/> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1"/> </o:shapelayout></xml><![endif]--> </head> <body lang=ES link=blue vlink="#954F72" style='tab-interval:35.4pt;word-wrap: break-word'> <div class=WordSection1> <p class=MsoNormal style='background:white'><b><span lang=EN-GB style='font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family: "Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-GB; mso-fareast-language:ES-TRAD'>Kim MJ, Kho HS. Efficacy of topical application of zinc compounds for oral mucosal diseases: A systematic review and meta-analysis. </span></b><b><span lang=PT-BR style='font-size:11.0pt; mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black; mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language: ES-TRAD'>Med Oral <span class=SpellE>Patol</span> Oral <span class=SpellE>Cir</span> Bucal. 2026 Jan 1;31 (1):e63-e72.<o:p></o:p></span></b></p> <p class=MsoNormal style='background:white'><span lang=PT-BR style='font-size: 13.5pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman"; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR; mso-fareast-language:ES-TRAD'><o:p>&nbsp;</o:p></span></p> <p class=MsoNormal style='background:white'><span lang=PT-BR style='font-size: 11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black; mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language: ES-TRAD'>&nbsp;</span><span lang=PT-BR style='font-size:13.5pt;font-family: "Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black; mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language: ES-TRAD'><o:p></o:p></span></p> <p class=MsoNormal style='background:white'><i><span lang=PT-BR style='font-size:10.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family: "Times New Roman";color:black;mso-font-kerning:0pt;mso-ligatures:none; mso-ansi-language:PT-BR;mso-fareast-language:ES-TRAD'>doi:10.4317/medoral.27549</span></i><span lang=PT-BR style='font-size:13.5pt;font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";color:black;mso-font-kerning:0pt; mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language:ES-TRAD'><o:p></o:p></span></p> <p class=MsoNormal style='background:white'><span style='font-size:10.0pt; font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman"; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-fareast-language:ES-TRAD'><a href="https://dx.doi.org/doi:10.4317/medoral.27549"><i><span lang=PT-BR style='mso-ansi-language:PT-BR'>https://dx.doi.org/doi:10.4317/medoral.27549</span></i></a></span><span lang=PT-BR style='font-size:13.5pt;font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";color:black;mso-font-kerning:0pt; mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language:ES-TRAD'><o:p></o:p></span></p> <div class=MsoNormal align=center style='text-align:center;background:white'><span style='font-size:10.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family: "Times New Roman";color:black;mso-font-kerning:0pt;mso-ligatures:none; mso-fareast-language:ES-TRAD;mso-no-proof:yes'> <hr size=1 width="99%" align=center> </span></div> <p class=MsoNoSpacing><span style='font-size:10.0pt'>1. Villanueva-Vilchis MD, López-Ríos P, García IM, Gaitán-Cepeda LA. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>Impact of oral mucosa lesions on the quality of life related to oral health: An <span class=SpellE>etiopathogenic</span> study. Med Oral <span class=SpellE>Patol</span> Oral Cir <span class=SpellE>Bucal</span>. 2016;21:e178-e184<br> <a href="https://doi.org/10.4317/medoral.20866">https://doi.org/10.4317/medoral.20866</a><br> PMid:26827060 PMCid:PMC4788796 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>2. <span class=SpellE>Cheruvathoor</span> DD, Thomas V, Kumar NR, Jose M. High prevalence of oral mucosal lesions in elderly: Call for revolutionizing geriatric dental care strategies. J Family Med Prim Care. 2020;9(8):4375-4380<br> <a href="https://doi.org/10.4103/jfmpc.jfmpc_51_20">https://doi.org/10.4103/jfmpc.jfmpc_51_20</a><br> PMid:33110863 PMCid:PMC7586582<br> <br> 3. N<span class=SpellE>ärhi</span> TO, <span class=SpellE>Meurman</span> JH, <span class=SpellE>Ainamo</span> A, <span class=SpellE>Nevalainen</span> JM, Schmidt-<span class=SpellE>Kaunisaho</span> KG, <span class=SpellE>Siukosaari</span> P, et al. Association between salivary flow rate and the use of systemic medication among 76-, 81-, and 86-year-old inhabitants in Helsinki, Finland. J Dent Res. 1992;71(12):1875-1880<br> <a href="https://doi.org/10.1177/00220345920710120401">https://doi.org/10.1177/00220345920710120401</a><br> PMid:1452886 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>4. Johansson AK, Johansson A, <span class=SpellE>Unell</span> L, <span class=SpellE>Ekbäck</span> G, <span class=SpellE>Ordell</span> S, Carlsson GE. Self-reported dry mouth in Swedish population samples aged 50, 65 and 75 years. <span class=SpellE>Gerodontology</span>. 2012;29(2):e107-e115<br> <a href="https://doi.org/10.1111/j.1741-2358.2010.00420.x">https://doi.org/10.1111/j.1741-2358.2010.00420.x</a> <br> PMid:22050189<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>5. <span class=SpellE>Bozdemir</span> E, Yilmaz HH, Orhan H. Oral mucosal lesions and risk factors in elderly dental patients. J Dent Res Dent Clin Dent Prospects. 2019;13(1):24-30<br> <a href="https://doi.org/10.15171/joddd.2019.004">https://doi.org/10.15171/joddd.2019.004</a><br> PMid:31217915 PMCid:PMC6571520 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>6. Soto AP, Meyer SL. Oral implications of polypharmacy in older adults. Clin <span class=SpellE>Geriatr</span> Med. 2023;39(2):273-293<br> <a href="https://doi.org/10.1016/j.cger.2023.01.008">https://doi.org/10.1016/j.cger.2023.01.008</a><br> PMid:37045533 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>7. Decani S, Federighi V, <span class=SpellE>Baruzzi</span> E, <span class=SpellE>Sardella</span> A, Lodi G. Iatrogenic Cushing's syndrome and topical steroid therapy: Case series and review of the literature. J <span class=SpellE>Dermatolog</span> Treat. 2014;25(6):495-500<br> <a href="https://doi.org/10.3109/09546634.2012.755252">https://doi.org/10.3109/09546634.2012.755252</a><br> PMid:23210698 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>8. <span class=SpellE>Frassinetti</span> S, <span class=SpellE>Bronzetti</span> G, <span class=SpellE>Caltavuturo</span> L, <span class=SpellE>Cini</span> M, Croce CD. The role of zinc in life: A review. J Environ <span class=SpellE>Pathol</span> <span class=SpellE>Toxicol</span> Oncol. 2006;25(3):597-610<br> <a href="https://doi.org/10.1615/JEnvironPatholToxicolOncol.v25.i3.40">https://doi.org/10.1615/JEnvironPatholToxicolOncol.v25.i3.40</a><br> PMid:17073562 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>9. Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: A review. Dermatol Res <span class=SpellE>Pract</span>. 2014;2014:709152<br> <a href="https://doi.org/10.1155/2014/709152">https://doi.org/10.1155/2014/709152</a><br> PMid:25120566 PMCid:PMC4120804 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>10. Bonaventura P, Benedetti G, <span class=SpellE>Albarède</span> F, <span class=SpellE>Miossec</span> P. Zinc and its role in immunity and inflammation. <span class=SpellE>Autoimmun</span> Rev. 2015;14(4):277-285<br> <a href="https://doi.org/10.1016/j.autrev.2014.11.008">https://doi.org/10.1016/j.autrev.2014.11.008</a><br> PMid:25462582 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>11. Kim MJ, Kang JH, Kho HS. Effects of zinc compounds on lysozyme, peroxidase, and </span><span style='font-size:10.0pt'>±</span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>-amylase from the perspective of oral health: A scoping review. Biol Trace Elem Res. 2024;202(9):3900-3909<br> <a href="https://doi.org/10.1007/s12011-023-03972-x">https://doi.org/10.1007/s12011-023-03972-x</a><br> PMid:38057484 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>12. Krebs NF. Update on zinc deficiency and excess in clinical pediatric practice. Ann <span class=SpellE>Nutr</span> <span class=SpellE>Metab</span>. 2013;62 Suppl 1:19-29<br> <a href="https://doi.org/10.1159/000348261">https://doi.org/10.1159/000348261</a><br> PMid:23689110 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>13. Livingstone C. Zinc: Physiology, deficiency, and parenteral nutrition. <span class=SpellE>Nutr</span> Clin <span class=SpellE>Pract</span>. 2015;30(3):371-382<br> <a href="https://doi.org/10.1177/0884533615570376">https://doi.org/10.1177/0884533615570376</a><br> PMid:25681484 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>14. Tamura Y. The role of zinc homeostasis in the prevention of diabetes mellitus and cardiovascular diseases. J <span class=SpellE>Atheroscler</span> <span class=SpellE>Thromb</span>. 2021;28(11):1109-1122<br> <a href="https://doi.org/10.5551/jat.RV17057">https://doi.org/10.5551/jat.RV17057</a><br> PMid:34148917 PMCid:PMC8592709 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>15. Komai M, <span class=SpellE>Goto</span> T, Suzuki H, Takeda T, Furukawa Y. Zinc deficiency and taste dysfunction: Contribution of carbonic anhydrase, a zinc-metalloenzyme, to normal taste sensation. <span class=SpellE>Biofactors</span>. 2000;12(1-4):65-70<br> <a href="https://doi.org/10.1002/biof.5520120111">https://doi.org/10.1002/biof.5520120111</a><br> PMid:11216508 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>16. Bao ZX, Yang XW, Shi J, Liu LX. Serum zinc levels in 368 patients with oral mucosal diseases: A preliminary study. Med Oral <span class=SpellE>Patol</span> Oral Cir <span class=SpellE>Bucal</span>. 2016;21(3):e335-e440<br> <a href="https://doi.org/10.4317/medoral.21079">https://doi.org/10.4317/medoral.21079</a><br> PMid:27031065 PMCid:PMC4867207 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>17. <span class=SpellE>Seyedmajidi</span> SA, <span class=SpellE>Seyedmajidi</span> M, <span class=SpellE>Moghadamnia</span> A, <span class=SpellE>Khani</span> Z, <span class=SpellE>Zahedpasha</span> S, <span class=SpellE>Jenabian</span> N, et al. Effect of zinc-deficient diet on oral tissues and periodontal indices in rats. Int J Mol Cell Med. 2014;3(2):81-87 <br> PMid:25035857<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>18. <span class=SpellE>Y1ld1r1myan</span> N, <span class=SpellE>Özalp</span> Ö, <span class=SpellE>^at1r</span> S, Altay MA, <span class=SpellE>Sindel</span> A. Recurrent aphthous stomatitis as a result of zinc deficiency. Oral Health <span class=SpellE>Prev</span> Dent. 2019;17(5):465-468<br> <a href="https://doi.org/10.3290/j.ohpd.a42736">https://doi.org/10.3290/j.ohpd.a42736</a><br> PMid:31268044<br> <br> 19. Plum LM, Rink L, <span class=SpellE>Haase</span> H. The essential toxin: Impact of zinc on human health. Int J Environ Res Public Health. 2010;7(4):1342-1365<br> <a href="https://doi.org/10.3390/ijerph7041342">https://doi.org/10.3390/ijerph7041342</a><br> PMid:20617034 PMCid:PMC2872358 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>20. <span class=SpellE>Uçkarde_</span> Y, <span class=SpellE>Tekçiçek</span> M, <span class=SpellE>Ozmert</span> EN, <span class=SpellE>Yurdakök</span> K. The effect of systemic zinc supplementation on oral health in low socioeconomic level children. Turk J <span class=SpellE>Pediatr</span>. 2009;51(5):424-428 <br> PMid:20112596<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>21. Tanaka M. Secretory function of the salivary gland in patients with taste disorders or xerostomia: Correlation with zinc deficiency. </span><span style='font-size:10.0pt'>Acta <span class=SpellE>Otolaryngol</span> <span class=SpellE>Suppl</span>. 2002;(546):134-141<br> <a href="https://doi.org/10.1080/00016480260046526">https://doi.org/10.1080/00016480260046526</a><br> PMid:12132611 <o:p></o:p></span></p> <p class=MsoNoSpacing><span style='font-size:10.0pt'>22. Cho GS, Han MW, Lee B, <span class=SpellE>Roh</span> JL, Choi SH, Cho KJ, et al. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>Zinc deficiency may be a cause of burning mouth syndrome as zinc replacement therapy has therapeutic effects. J Oral <span class=SpellE>Pathol</span> Med. 2010;39(9):722-727<br> <a href="https://doi.org/10.1111/j.1600-0714.2010.00914.x">https://doi.org/10.1111/j.1600-0714.2010.00914.x</a><br> PMid:20618611 <o:p></o:p></span></p> <p class=MsoNoSpacing><span style='font-size:10.0pt'>23. <span class=SpellE>Sharquie</span> KE, <span class=SpellE>Najim</span> RA, Al-<span class=SpellE>Hayani</span> RK, Al-<span class=SpellE>Nuaimy</span> AA, <span class=SpellE>Maroof</span> DM. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>The therapeutic and prophylactic role of oral zinc sulfate in management of recurrent aphthous stomatitis compared with dapsone. Saudi Med J. 2008;29(5):734-738 PMid:18454224<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>24. U.S. Food and Drug Administration. Database of Select Committee on GRAS Substances (SCOGS) reviews. Accessed 2025 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>25. Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. </span><span lang=PT-BR style='font-size:10.0pt;mso-ansi-language: PT-BR'>Br J Dermatol. 1981;104(2):191-194<br> <a href="https://doi.org/10.1111/j.1365-2133.1981.tb00044.x">https://doi.org/10.1111/j.1365-2133.1981.tb00044.x</a><br> PMid:7213551 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>26. <span class=SpellE>Hoogendoorn</span> H, <span class=SpellE>Piessens</span> JP. Treatment of aphthous patients by enhancement of the salivary peroxidase system. J Oral <span class=SpellE>Pathol</span>. 1987;16(8):425-427<br> <a href="https://doi.org/10.1111/j.1600-0714.1987.tb02080.x">https://doi.org/10.1111/j.1600-0714.1987.tb02080.x</a><br> PMid:2826739 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>27. <span class=SpellE>Mehdipour</span> M, <span class=SpellE>Taghavi</span> <span class=SpellE>Zenouz</span> A, <span class=SpellE>Bahramian</span> A, Yazdani J, <span class=SpellE>Pouralibaba</span> F, Sadr K. Comparison of mouthwashes with and without zinc and fluocinolone on the healing of erosive oral lichen planus. J Dent Res Dent Clin Dent Prospects. 2010;4(1):25-28 <br> <a href="https://doi.org/10.5681/joddd.2010.007">https://doi.org/10.5681/joddd.2010.007</a><br> PMid:22991591<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>28. <span class=SpellE>Mehdipour</span> M, <span class=SpellE>Taghavi</span> <span class=SpellE>Zenooz</span> A, <span class=SpellE>Asvadi</span> <span class=SpellE>Kermani</span> I, <span class=SpellE>Hosseinpour</span> A. Comparison of zinc sulfate and chlorhexidine gluconate mouthwashes in the prevention of chemotherapy-induced oral mucositis. Daru. 2011;19(1):71-73 <br> PMid:22615642<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>29. <span class=SpellE>Mehdipour</span> M, <span class=SpellE>Taghavi</span> <span class=SpellE>Zenooz</span> A, <span class=SpellE>Sohrabi</span> A, <span class=SpellE>Gholizadeh</span> N, <span class=SpellE>Bahramian</span> A, Jamali Z. Effect of triamcinolone ointment and mouthwash with or without zinc on healing of aphthous stomatitis lesions. J Dent Res Dent Clin Dent Prospects. 2016;10(2):87-91<br> <a href="https://doi.org/10.15171/joddd.2016.014">https://doi.org/10.15171/joddd.2016.014</a><br> PMid:27429724 PMCid:PMC4946004 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>30. Chaitanya N, <span class=SpellE>Badam</span> R, <span class=SpellE>Aryasri</span> AS, <span class=SpellE>Pallarla</span> S, <span class=SpellE>Garlpati</span> K, <span class=SpellE>Akhila</span> M, et al. Efficacy of improvised topical zinc (1%) Ora-Base on oral mucositis during cancer chemo-radiation: A randomized study. J <span class=SpellE>Nutr</span> Sci <span class=SpellE>Vitaminol</span> (Tokyo). 2020;66(2):93-97<br> <a href="https://doi.org/10.3177/jnsv.66.93">https://doi.org/10.3177/jnsv.66.93</a><br> PMid:32350185 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>31. <span class=SpellE>Ghorbani</span> A, Akbari J, <span class=SpellE>Boorboor</span> M, <span class=SpellE>Nekoukar</span> Z, <span class=SpellE>Eslami</span> G. Zinc sulfate mucoadhesive formulation for recurrent aphthous stomatitis: Randomized double-blind placebo-controlled trial. BMC Oral Health. 2020;20(1):212<br> <a href="https://doi.org/10.1186/s12903-020-01194-4">https://doi.org/10.1186/s12903-020-01194-4</a><br> PMid:32723352 PMCid:PMC7385976 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>32. <span class=SpellE>Niculita</span> OO, <span class=SpellE>Jercan</span> CG, <span class=SpellE>Colita</span> A, <span class=SpellE>Tanase</span> AD, <span class=SpellE>Colita</span> A. Polyvinylpyrrolidone-Zn gluconate and taurine for prevention of oral mucositis in hematological patients. Rev <span class=SpellE>Chim</span>. 2020;71(8):195-205<br> <a href="https://doi.org/10.37358/RC.20.8.8280">https://doi.org/10.37358/RC.20.8.8280</a><o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>33. <span class=SpellE>Oshvandi</span> K, <span class=SpellE>Vafaei</span> SY, <span class=SpellE>Kamallan</span> SR, <span class=SpellE>Khazaei</span> S, <span class=SpellE>Ranjbar</span> H, Mohammadi F. Zinc chloride mouthwash effectiveness on oral mucositis and weight in cancer patients receiving chemotherapy. BMC Oral Health. 2021;21(1):364<br> <a href="https://doi.org/10.1186/s12903-021-01706-w">https://doi.org/10.1186/s12903-021-01706-w</a><br> PMid:34294072 PMCid:PMC8296564 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>34. Mohammadi F, <span class=SpellE>Oshvandi</span> K, <span class=SpellE>Kamallan</span> SR, <span class=SpellE>Khazaei</span> S, <span class=SpellE>Ranjbar</span> H, Ahmadi-<span class=SpellE>Motamayel</span> F, et al. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in oral mucositis and quality of life during chemotherapy. <span class=SpellE>Nurs</span> Open. 2022;9(3):1602-1611<br> <a href="https://doi.org/10.1002/nop2.1168">https://doi.org/10.1002/nop2.1168</a><br> PMid:35170247 PMCid:PMC8994952 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>35. <span class=SpellE>Alipour</span> M, <span class=SpellE>Habibivand</span> E, <span class=SpellE>Sekhavati</span> S, Aghazadeh Z, <span class=SpellE>Ranjkesh</span> M, <span class=SpellE>Ramezani</span> S, et al. Therapeutic effects of nanofibrous mat containing mycophenolate mofetil on oral lichen planus. <span class=SpellE>Biomater</span> <span class=SpellE>Investig</span> Dent. 2023;10(1):2283177<br> <a href="https://doi.org/10.1080/26415275.2023.2283177">https://doi.org/10.1080/26415275.2023.2283177</a><br> PMid:38204471 PMCid:PMC10763882 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>36. Deb B, Santhanam V, <span class=SpellE>Narayanamurthy</span> U, <span class=SpellE>Raizada</span> P, Jain R, Murugesan S. Efficacy and safety of zinc carnosine and lignocaine for oral mucositis: Phase 3 study. Int J Sci Res Dent Med Sci. 2023;5(4):181-187 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>37. <span class=SpellE>Sahebnasagh</span> M, <span class=SpellE>Aksi</span> V, <span class=SpellE>Eslami</span> F, <span class=SpellE>Lashkardoost</span> H, <span class=SpellE>Kasaian</span> J, <span class=SpellE>Golmohammadzadeh</span> S, et al. Zinc and polyherbal mouthwash for prevention of radiotherapy-related oral mucositis: Double-blind randomized clinical trial. <span class=SpellE>Eur</span> J Med Res. 2023;28(1):109<br> <a href="https://doi.org/10.1186/s40001-023-01015-8">https://doi.org/10.1186/s40001-023-01015-8</a><br> PMid:36864527 PMCid:PMC9979417 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>38. Patil K, Sanjay CJ, Mahima VG, Renuka Devi KR, Ramesh AR, Shiny A. Zinc sulfate vs <span class=SpellE>benzydamine</span> mouthwash in radiation-induced oral mucositis. J Indian <span class=SpellE>Acad</span> Oral Med <span class=SpellE>Radiol</span>. 2024;36(1):2-6<br> <a href="https://doi.org/10.4103/jiaomr.jiaomr_20_23">https://doi.org/10.4103/jiaomr.jiaomr_20_23</a><br> <br> 39. Tian X, Liu XL, Pi YP, Chen H, Chen WQ. Oral zinc sulfate for prevention and treatment of chemotherapy-induced oral mucositis: Meta-analysis. Front Oncol. 2018;8:484<br> <a href="https://doi.org/10.3389/fonc.2018.00484">https://doi.org/10.3389/fonc.2018.00484</a><br> PMid:30510915 PMCid:PMC6252385 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>40. Shuai T, Tian X, Shi B, Chen H, Liu XL, Yi LJ, et al. Prophylaxis with oral zinc sulfate against radiation-induced oral mucositis: Systematic review and meta-analysis. Front Oncol. 2019;9:165<br> <a href="https://doi.org/10.3389/fonc.2019.00165">https://doi.org/10.3389/fonc.2019.00165</a><br> PMid:30967996 PMCid:PMC6438884 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>41. Page MJ, McKenzie JE, <span class=SpellE>Bossuyt</span> PM, <span class=SpellE>Boutron</span> I, Hoffmann TC, Mulrow CD, et al. PRISMA 2020 statement: Updated guideline for systematic reviews. BMJ. 2021;372:n71<br> <a href="https://doi.org/10.1136/bmj.n71">https://doi.org/10.1136/bmj.n71</a><br> PMid:33782057 PMCid:PMC8005924 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>42. Sterne JAC, <span class=SpellE>Savovi</span> J, Page MJ, <span class=SpellE>Elbers</span> RG, <span class=SpellE>Blencowe</span> NS, <span class=SpellE>Boutron</span> I, et al. <span class=SpellE>RoB</span> 2: Revised risk-of-bias tool for randomized trials. BMJ. 2019;366:l4898<br> <a href="https://doi.org/10.1136/bmj.l4898">https://doi.org/10.1136/bmj.l4898</a><br> PMid:31462531 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>43. Villa A, <span class=SpellE>Sonis</span> ST. Pharmacotherapy for cancer regimen-related oral mucositis. Expert <span class=SpellE>Opin</span> <span class=SpellE>Pharmacother</span>. 2016;17(13):1801-1807<br> <a href="https://doi.org/10.1080/14656566.2016.1217993">https://doi.org/10.1080/14656566.2016.1217993</a><br> PMid:27477002 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>44. McGuire DB, <span class=SpellE>Altomonte</span> V, Peterson DE, Wingard JR, Jones RJ, <span class=SpellE>Grochow</span> LB. Patterns of mucositis and pain during chemotherapy and bone marrow transplantation. Oncol <span class=SpellE>Nurs</span> Forum. 1993;20(10):1493-1502<br> PMid:8278277<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>45. <span class=SpellE>Elting</span> LS, <span class=SpellE>Cooksley</span> C, Chambers M, Cantor SB, Manzullo E, Rubenstein EB. Clinical and economic outcomes of chemotherapy-induced mucositis. Cancer. 2003;98(7):1531-1539<br> <a href="https://doi.org/10.1002/cncr.11671">https://doi.org/10.1002/cncr.11671</a><br> PMid:14508842 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>46. <span class=SpellE>Elad</span> S, Cheng KKF, Lalla RV, <span class=SpellE>Yarom</span> N, Hong C, Logan RM, et al. MASCC/ISOO clinical practice guidelines for management of mucositis. Cancer. 2020;126(19):4423-4431<br> <a href="https://doi.org/10.1002/cncr.33100">https://doi.org/10.1002/cncr.33100</a><br> PMid:32786044 PMCid:PMC7540329 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>47. <span class=SpellE>Sonis</span> ST. The pathobiology of mucositis. Nat Rev Cancer. 2004;4(4):277-284<br> <a href="https://doi.org/10.1038/nrc1318">https://doi.org/10.1038/nrc1318</a><br> PMid:15057287 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>48. Al-<span class=SpellE>Dasooqi</span> N, <span class=SpellE>Sonis</span> ST, Bowen JM, Bateman E, <span class=SpellE>Blijlevens</span> N, Gibson RJ, et al. Emerging evidence on the pathobiology of mucositis. Support Care Cancer. 2013;21(7):3233-3241<br> </span><span lang=PT-BR style='font-size:10.0pt;mso-ansi-language:PT-BR'><a href="https://doi.org/10.1007/s00520-013-1900-x"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1007/s00520-013-1900-x</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> </span><span lang=PT-BR style='font-size:10.0pt;mso-ansi-language:PT-BR'><a href="https://doi.org/10.1007/s00520-013-1810-y"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1007/s00520-013-1810-y</span></a><br> PMid:23604521</span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'><br> <br> 49. </span><span class=SpellE><span lang=PT-BR style='font-size:10.0pt; mso-ansi-language:PT-BR'>Skrovanek</span></span><span lang=PT-BR style='font-size:10.0pt;mso-ansi-language:PT-BR'> S, <span class=SpellE>DiGuilio</span> K, <span class=SpellE>Bailey</span> R, Huntington W, <span class=SpellE>Urbas</span> R, <span class=SpellE>Mayilvaganan</span> B, et al. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>Zinc and gastrointestinal disease. World J <span class=SpellE>Gastrointest</span> <span class=SpellE>Pathophysiol</span>. 2014;5(4):496-513<br> <a href="https://doi.org/10.4291/wjgp.v5.i4.496">https://doi.org/10.4291/wjgp.v5.i4.496</a><br> PMid:25400994 PMCid:PMC4231515 </span><span lang=PT-BR style='font-size:10.0pt; mso-ansi-language:PT-BR'><o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>50. Scully C, Porter S. Recurrent aphthous stomatitis: Etiology, pathogenesis, and management. J Oral <span class=SpellE>Pathol</span> Med. 1989;18(1):21-27<br> <a href="https://doi.org/10.1111/j.1600-0714.1989.tb00727.x">https://doi.org/10.1111/j.1600-0714.1989.tb00727.x</a><br> PMid:2664131 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>51. <span class=SpellE>Sugerman</span> PB, Savage NW, Walsh LJ, Zhao ZZ, Zhou XJ, Khan A, et al. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med. 2002;13(4):350-365<br> <a href="https://doi.org/10.1177/154411130201300405">https://doi.org/10.1177/154411130201300405</a><br> PMid:12191961 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>52. <span class=SpellE>Baek</span> K, Choi Y. The microbiology of oral lichen planus. </span><span lang=PT-BR style='font-size:10.0pt;mso-ansi-language: PT-BR'>Mol Oral Microbiol. 2018;33(1):22-28<br> <a href="https://doi.org/10.1111/omi.12197">https://doi.org/10.1111/omi.12197</a><br> </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>PMid:28869787 </span><span lang=PT-BR style='font-size:10.0pt;mso-ansi-language:PT-BR'><o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>53. Kim Y, Chang JY, Kim YY, Lee JW, Kho HS. Effects of zinc compounds on enzymatic activity and antifungal effects. Biol Trace Elem Res. 2024;202(12):5850-5862<br> <a href="https://doi.org/10.1007/s12011-024-04110-x">https://doi.org/10.1007/s12011-024-04110-x</a><br> PMid:38376730 PMCid:PMC11502591 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>54. Hwang YJ, Kim YY, Chang JY, Kho HS. Candidacidal activity of zinc compounds depending on incubation time, pH, and ionic strength. J Dent Sci. 2025;20(2):885-894<br> <a href="https://doi.org/10.1016/j.jds.2024.09.002">https://doi.org/10.1016/j.jds.2024.09.002</a><br> PMid:40224092 PMCid:PMC11993022 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>55. Park YJ, Kim YY, Chang JY, Kho HS. In vitro effects of zinc compounds on salivary antimicrobial candidacidal activity. Int Dent J. 2025;75(2):1261-1268<br> <a href="https://doi.org/10.1016/j.identj.2024.09.006">https://doi.org/10.1016/j.identj.2024.09.006</a><br> PMid:39384441 PMCid:PMC11976611<o:p></o:p></span></p> </div> </body> </html>