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<div class=WordSection1> <p class=MsoNormal style='background:white'><b><span lang=EN-GB style='font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family: "Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-GB; mso-fareast-language:ES-TRAD'>Gil-Montoya JA, <span class=SpellE>Gerez</span> Muñoz MJ, <span class=SpellE>Triviño</span>-Ibáñez EM, <span class=SpellE>Rosel</span> E, Bravo M, <span class=SpellE>Rómero-Fábrega</span> JC, Morales-Santana S, Gómez-Río M. Relationship between salivary lactoferrin level and brain amyloid load in periodontal and non-periodontal subjects. Med Oral <span class=SpellE>Patol</span> Oral Cir <span class=SpellE>Bucal</span>. 2026 Jan 1;31 (1):e118-e123.</span></b><b><span lang=PT-BR style='font-size:11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family: "Times New Roman";mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR; mso-fareast-language:ES-TRAD'><o:p></o:p></span></b></p> <p class=MsoNormal style='background:white'><span lang=PT-BR style='font-size: 13.5pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman"; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR; mso-fareast-language:ES-TRAD'><o:p>&nbsp;</o:p></span></p> <p class=MsoNormal style='background:white'><span lang=PT-BR style='font-size: 11.0pt;mso-ascii-font-family:Calibri;mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Calibri;mso-bidi-font-family:Calibri;color:black; mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language: ES-TRAD'>&nbsp;</span><span lang=PT-BR style='font-size:13.5pt;font-family: "Times New Roman",serif;mso-fareast-font-family:"Times New Roman";color:black; mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language: ES-TRAD'><o:p></o:p></span></p> <p class=MsoNormal style='background:white'><i><span lang=PT-BR style='font-size:10.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family: "Times New Roman";color:black;mso-font-kerning:0pt;mso-ligatures:none; mso-ansi-language:PT-BR;mso-fareast-language:ES-TRAD'>doi:10.4317/medoral.27612</span></i><span lang=PT-BR style='font-size:13.5pt;font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";color:black;mso-font-kerning:0pt; mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language:ES-TRAD'><o:p></o:p></span></p> <p class=MsoNormal style='background:white'><span style='font-size:10.0pt; font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman"; color:black;mso-font-kerning:0pt;mso-ligatures:none;mso-fareast-language:ES-TRAD'><a href="https://dx.doi.org/doi:10.4317/medoral.27612"><i><span lang=PT-BR style='mso-ansi-language:PT-BR'>https://dx.doi.org/doi:10.4317/medoral.27612</span></i></a></span><span lang=PT-BR style='font-size:13.5pt;font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";color:black;mso-font-kerning:0pt; mso-ligatures:none;mso-ansi-language:PT-BR;mso-fareast-language:ES-TRAD'><o:p></o:p></span></p> <div class=MsoNormal align=center style='text-align:center;background:white'><span style='font-size:10.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family: "Times New Roman";color:black;mso-font-kerning:0pt;mso-ligatures:none; mso-fareast-language:ES-TRAD;mso-no-proof:yes'> <hr size=1 width="99%" align=center> </span></div> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>1. Olsen I. Possible effects of <span class=SpellE>Porphyromonas</span> <span class=SpellE>gingivalis</span> on the blood-brain barrier in Alzheimer's disease. Expert Rev Anti Infect <span class=SpellE>Ther</span>. 2021;19(11):1367-1371<br> <a href="https://doi.org/10.1080/14787210.2021.1925540">https://doi.org/10.1080/14787210.2021.1925540</a><br> PMid:33938372 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>2. Cai Z, <span class=SpellE>Qiao</span> PF, Wan CQ, Cai M, Zhou NK, Li Q. Role of blood-brain barrier in Alzheimer's disease. J <span class=SpellE>Alzheimers</span> Dis. 2018;63(4):1223-1234<br> <a href="https://doi.org/10.3233/JAD-180098">https://doi.org/10.3233/JAD-180098</a><br> PMid:29782323 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>3. <span class=SpellE>Darveau</span> RP, <span class=SpellE>Hajishengallis</span> G, Curtis MA. <span class=SpellE>Porphyromonas</span> <span class=SpellE>gingivalis</span> as a potential community activist for disease. J Dent Res. 2012;91(9):816-820<br> <a href="https://doi.org/10.1177/0022034512453589">https://doi.org/10.1177/0022034512453589</a><br> PMid:22772362 PMCid:PMC3420389 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>4. <span class=SpellE>Ilievski</span> V, <span class=SpellE>Zuchowska</span> PK, Green SJ, Toth PT, <span class=SpellE>Ragozzino</span> ME, Le K, et al. Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice. <span class=SpellE>PLoS</span> One. 2018;13(10):e0204941<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.1371/journal.pone.0204941"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1371/journal.pone.0204941</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:30281647 PMCid:PMC6169940 <o:p></o:p></span></p> <p class=MsoNoSpacing><span style='font-size:10.0pt'>5. <span class=SpellE>Beydoun</span> MA, <span class=SpellE>Beydoun</span> HA, <span class=SpellE>Hossain</span> S, El-<span class=SpellE>Hajj</span> ZW, Weiss J, <span class=SpellE>Zonderman</span> AB. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>Clinical and bacterial markers of periodontitis and their association with incident all-cause and Alzheimer's disease dementia in a large national survey. J <span class=SpellE>Alzheimers</span> Dis. 2020;75(1):157-172<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.3233/JAD-200064"><span lang=EN-US style='mso-ansi-language: EN-US'>https://doi.org/10.3233/JAD-200064</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:32280099 PMCid:PMC11008556 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>6. <span class=SpellE>Laugisch</span> O, <span class=SpellE>Johnen</span> A, Maldonado A, Ehmke B, <span class=SpellE>Bürgin</span> W, Olsen I, et al. Periodontal pathogens and associated intrathecal antibodies in early stages of Alzheimer's disease. J <span class=SpellE>Alzheimers</span> Dis. 2018;66(1):105-114<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.3233/JAD-180620"><span lang=EN-US style='mso-ansi-language: EN-US'>https://doi.org/10.3233/JAD-180620</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:30223397 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>7. Olsen I, <span class=SpellE>Singhrao</span> SK. Can oral infection be a risk factor for Alzheimer's disease? J Oral <span class=SpellE>Microbiol</span>. 2015;7:29143<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.3402/jom.v7.29143"><span lang=EN-US style='mso-ansi-language: EN-US'>https://doi.org/10.3402/jom.v7.29143</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:26385886 PMCid:PMC4575419 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>8. <span class=SpellE>Dominy</span> SS, Lynch C, <span class=SpellE>Ermini</span> F, <span class=SpellE>Benedyk</span> M, <span class=SpellE>Marczyk</span> A, <span class=SpellE>Konradi</span> A, et al. <span class=SpellE>Porphyromonas</span> <span class=SpellE>gingivalis</span> in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019;5(1):eaau3333<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.1126/sciadv.aau3333"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1126/sciadv.aau3333</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:30746447 PMCid:PMC6357742 <o:p></o:p></span></p> <p class=MsoNoSpacing><span style='font-size:10.0pt'>9. <span class=SpellE>Gonzalez-Sanchez</span> M, <span class=SpellE>Bartolome</span> F, Antequera D, Puertas-Martin V, <span class=SpellE>Gonzalez</span> P, <span class=SpellE>Gomez</span>-Grande A, et al. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>Decreased salivary lactoferrin levels are specific to Alzheimer's disease. <span class=SpellE>EBioMedicine</span>. 2020;57:102834<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.1016/j.ebiom.2020.102834"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1016/j.ebiom.2020.102834</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:32586758 PMCid:PMC7378957 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>10. <span class=SpellE>Municio</span> C, <span class=SpellE>Carro</span> E. Implication of salivary lactoferrin and periodontal-mediated infections in Alzheimer's disease. Neural Regen Res. 2023;18(12):2691-2692<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.4103/1673-5374.373712"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.4103/1673-5374.373712</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:37449625 PMCid:PMC10358677 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>11. Antequera D, <span class=SpellE>Carrero</span> L, Gonzalez-Sanchez M, <span class=SpellE>Cantero</span> JL, <span class=SpellE>Orive</span> G, <span class=SpellE>Municio</span> C, <span class=SpellE>Carro</span> E. Reduced salivary lactoferrin levels in early-onset <span class=SpellE>alzheimer's</span> disease. Aging Dis. 2024;15(3):945-94</span><span style='font-size:10.0pt'>7<br> <a href="https://doi.org/10.14336/AD.2023.0819">https://doi.org/10.14336/AD.2023.0819</a><br> PMid:37815910</span><span style='font-size:10.0pt;mso-ansi-language:EN-US'> </span><span style='font-size:10.0pt'><o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>12. <span class=SpellE>Winblad</span> B, Palmer K, <span class=SpellE>Kivipelto</span> M, <span class=SpellE>Jelic</span> V, <span class=SpellE>Fratiglioni</span> L, <span class=SpellE>Wahlund</span> LO, et al. Mild cognitive impairment-beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment. J Intern Med. 2004;256(3):240-246<br> <a href="https://doi.org/10.1111/j.1365-2796.2004.01380.x">https://doi.org/10.1111/j.1365-2796.2004.01380.x</a><br> PMid:15324367 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>13. Dubois B, Hampel H, Feldman HH, <span class=SpellE>Scheltens</span> P, <span class=SpellE>Aisen</span> P, <span class=SpellE>Andrieu</span> S, et al. Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria. <span class=SpellE>Alzheimers</span> Dement. </span><span style='font-size:10.0pt'>2016;12(3):292-323<br> <a href="https://doi.org/10.1016/j.jalz.2016.02.002">https://doi.org/10.1016/j.jalz.2016.02.002</a><br> PMid:27012484 PMCid:PMC6417794 <o:p></o:p></span></p> <p class=MsoNoSpacing><span style='font-size:10.0pt'>14. <span class=SpellE>Solis</span>-Urra P, Molina-Hidalgo C, <span class=SpellE>Garcia</span>-Rivero Y, Costa-<span class=SpellE>Rodriguez</span> C, Mora-<span class=SpellE>Gonzalez</span> J, <span class=SpellE>Fernandez-Gamez</span> B, et al. </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>Active gains in brain using exercise during aging (AGUEDA): Protocol for a randomized controlled trial. Front Hum <span class=SpellE>Neurosci</span>. 2023;17:1168549<br> <a href="https://doi.org/10.3389/fnhum.2023.1168549">https://doi.org/10.3389/fnhum.2023.1168549</a><br> PMid:37284481 PMCid:PMC10239947 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>15. <span class=SpellE>Minoshima</span> S, <span class=SpellE>Drzezga</span> AE, Barthel H, <span class=SpellE>Bohnen</span> N, <span class=SpellE>Djekidel</span> M, Lewis DH, et al. SNMMI procedure standard/EANM practice guideline for amyloid PET imaging of the brain 1.0. J <span class=SpellE>Nucl</span> Med. 2016;57(8):1316-1322<br> <a href="https://doi.org/10.2967/jnumed.116.174615">https://doi.org/10.2967/jnumed.116.174615</a><br> PMid:27481605 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>16. Sabri O, <span class=SpellE>Seibyl</span> J, Rowe C, Barthel H. Beta-amyloid imaging with <span class=SpellE>florbetaben</span>. Clin <span class=SpellE>Transl</span> Imaging. 2015;3(1):13-26<br> <a href="https://doi.org/10.1007/s40336-015-0102-6">https://doi.org/10.1007/s40336-015-0102-6</a><br> PMid:25741488 PMCid:PMC4339690 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>17. Barthel H, Gertz HJ, <span class=SpellE>Dresel</span> S, Peters O, <span class=SpellE>Bartenstein</span> P, <span class=SpellE>Buerger</span> K, et al. Cerebral amyloid-beta PET with <span class=SpellE>florbetaben</span> (18F) in patients with Alzheimer's disease and healthy controls: A <span class=SpellE>multicentre</span> phase 2 diagnostic study. Lancet Neurol. 2011;10(5):424-435<br> <a href="https://doi.org/10.1016/S1474-4422(11)70077-1">https://doi.org/10.1016/S1474-4422(11)70077-1</a><br> PMid:21481640 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>18. <span class=SpellE>Tonetti</span> MS, Greenwell H, <span class=SpellE>Kornman</span> KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin <span class=SpellE>Periodontol</span>. 2019;46(7):787 <br> <a href="https://doi.org/10.1111/jcpe.12945">https://doi.org/10.1111/jcpe.12945</a><br> PMid:29926495<o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>19. <span class=SpellE>Kruzel</span> ML, Zimecki M, Actor JK. Lactoferrin in a context of inflammation-induced pathology. Front Immunol. 2017;8:1438<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.3389/fimmu.2017.01438"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.3389/fimmu.2017.01438</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:29163511 PMCid:PMC5681489 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>20. <span class=SpellE>Fulop</span> T, <span class=SpellE>Itzhaki</span> RF, <span class=SpellE>Balin</span> BJ, <span class=SpellE>Miklossy</span> J, Barron AE. Role of microbes in the development of Alzheimer's disease: State of the art-An international symposium presented at the 2017 IAGG Congress in San Francisco. Front Genet. 2018;9:362<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.3389/fgene.2018.00362"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.3389/fgene.2018.00362</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:30250480 PMCid:PMC6139345 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>21. <span class=SpellE>Carro</span> E, Bartolome F, Bermejo-Pareja F, <span class=SpellE>Villarejo-Galende</span> A, Molina JA, Ortiz P, et al. Early diagnosis of mild cognitive impairment and Alzheimer's disease based on salivary lactoferrin. <span class=SpellE>Alzheimers</span> Dement (<span class=SpellE>Amst</span>). 2017;8:131-138<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.1016/j.dadm.2017.04.002"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1016/j.dadm.2017.04.002</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:28649597 PMCid:PMC5470603 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>22. Bermejo-Pareja F, Del Ser T, <span class=SpellE>Valenti</span> M, de la Fuente M, Bartolome F, <span class=SpellE>Carro</span> E. Salivary lactoferrin as biomarker for Alzheimer's disease: Brain-immunity interactions. <span class=SpellE>Alzheimers</span> Dement. 2020;16(8):1196-1204<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.1002/alz.12107"><span lang=EN-US style='mso-ansi-language: EN-US'>https://doi.org/10.1002/alz.12107</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:32543760 PMCid:PMC7984071 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>23. <span class=SpellE>Ramenzoni</span> LL, Hofer D, <span class=SpellE>Solderer</span> A, <span class=SpellE>Wiedemeier</span> D, <span class=SpellE>Attin</span> T, <span class=SpellE>Schmidlin</span> PR. Origin of MMP-8 and lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva. BMC Oral Health. 2021;21(1):385<br> </span><span style='font-size:10.0pt'><a href="https://doi.org/10.1186/s12903-021-01743-5"><span lang=EN-US style='mso-ansi-language:EN-US'>https://doi.org/10.1186/s12903-021-01743-5</span></a></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><br> PMid:34353321 PMCid:PMC8340507 <o:p></o:p></span></p> <p class=MsoNoSpacing><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>24. <span class=SpellE>Gleerup</span> HS, Jensen CS, <span class=SpellE>Hogh</span> P, <span class=SpellE>Hasselbalch</span> SG, Simonsen AH. Lactoferrin in cerebrospinal fluid and saliva is not a diagnostic biomarker for Alzheimer's disease in a mixed memory clinic population. </span><span class=SpellE><span style='font-size:10.0pt'>EBioMedicine</span></span><span style='font-size:10.0pt'>. 2021;67:103361<br> <a href="https://doi.org/10.1016/j.ebiom.2021.103361">https://doi.org/10.1016/j.ebiom.2021.103361</a><br> PMid:33975253 PMCid:PMC8122152<o:p></o:p></span></p> </div> </body> </html>