Alsaegh MA, Shehhi YIA, Shetty SR, Mahmoud O, Narayanan JK, Varma SR. Comparative analysis of salivary IL-4 and CXCL6 dynamics following tooth extraction in diabetic and non-diabetic patients. Med Oral Patol Oral Cir Bucal. 2026 Jul 1;31 (4):e609-15.
doi:10.4317/medoral.28058
https://dx.doi.org/doi:10.4317/medoral.28058
1.
Chuhuaicura P, Rodríguez-Niklitschek C, Oporto GH, Salazar LA.
Distinct Molecular Mechanisms in Oral Mucosal Wound Healing:
Translational Insights and Future Directions. Int J Mol Sci.
2025;26:10660. |
|
|
|
2.
Dasari N, Jiang A, Skochdopole A, Chung J, Reece EM, Vorstenbosch
J, et al. Updates in Diabetic Wound Healing, Inflammation, and
Scarring. Semin Plast Surg.
2021;35:153-8. |
|
|
|
3.
Ridiandries A, Tan JTM, Bursill CA. The Role of Chemokines in
Wound Healing. Int J Mol Sci.
2018;19:3217. |
|
|
|
4.
Pan K, Li Q, Guo Z, Li Z. Healing action of Interleukin-4 (IL-4)
in acute and chronic inflammatory conditions: Mechanisms and
therapeutic strategies. Pharmacol Ther.
2025;265:108760. |
|
|
|
5.
Munaò S, Armeli A, Bonfiglio D, Iaconis A, Calabrese G.
Immune-Guided Bone Healing: The Role of Osteoimmunity in Tissue
Engineering Approaches. Int J Mol Sci. 2025;
26:11642. |
|
|
|
6.
Hartman ME, O'Connor JC, Godbout JP, Minor KD, Mazzocco VR, Freund
GG. Insulin receptor substrate-2-dependent interleukin-4 signaling
in macrophages is impaired in two models of type 2 diabetes
mellitus. J Biol Chem.
2004;279(27):28045-50. |
|
|
|
7.
Asif R, Khalid A, Mercantepe T, Klisic A, Rafaqat S, Rafaqat S, et
al. Role of Interleukins in Type 1 and Type 2 Diabetes.
Diagnostics (Basel). 2025;
15:1906. |
|
|
|
8.
Kebschull M, Demmer R, Behle JH, Pollreisz A, Heidemann J, Belusko
PB, et al. Granulocyte chemotactic protein 2 (gcp-2/cxcl6)
complements interleukin-8 in periodontal disease. J Periodontal
Res.
2009;44:465-71. |
|
|
|
9.
Wang X, Li J, Wang Z, Deng A. Wound exudate CXCL6: Potential
biomarker for wound healing of diabetic foot ulcers. Biomark Med.
2019;13:167-74. |
|
|
|
10.
Dowey R, Iqbal A, Heller SR, Sabroe I, Prince LR. A Bittersweet
Response to Infection in Diabetes; Targeting Neutrophils to Modify
Inflammation and Improve Host Immunity. Front Immunol.
2021;12:678771. |
|
|
|
11.
Roy R, Zayas J, Singh SK, Delgado K, Wood SJ, Mohamed MF, et al.
Overriding impaired FPR chemotaxis signaling in diabetic
neutrophil stimulates infection control in murine diabetic wound.
Elife.
2022;11:e72071. |
|
|
|
12.
Shinjo T, Onizuka S, Zaitsu Y, Ishikado A, Park K, Li Q, et al.
Dysregulation of CXCL1 Expression and Neutrophil Recruitment in
Insulin Resistance and Diabetes-Related Periodontitis in Male
Mice. Diabetes.
2023;72:986-98. |
|
|
|
13.
Xue C, Chen K, Gao Z, Bao T, Dong L, Zhao L, et al. Common
mechanisms underlying diabetic vascular complications: Focus on
the interaction of metabolic disorders, immuno-inflammation, and
endothelial dysfunction. Cell Commun Signal.
2023;21(1):298. |
|
|
|
14.
Al Shehhi YI, Elemam NM, Alsaegh MA. The response of salivary
proinflammatory biomarkers to tooth extraction in individuals with
type II diabetes mellitus. BMC Oral Health.
2024;24:250. |
|
|
|
15.
Udeabor SE, Heselich A, Al-Maawi S, Alqahtani AF, Sader R,
Ghanaati S. Current Knowledge on the Healing of the Extraction
Socket: A Narrative Review. Bioengineering (Basel).
2023;10:1145. |
|
|
|
16.
Tatarakis N, Kinney JS, Inglehart M, Braun TM, Shelburne C, Lang
NP, et al. Clinical, microbiological, and salivary biomarker
profiles of dental implant patients with type 2 diabetes. Clin
Oral Implants Res.
2014;25:803-12. |
|
|
|
17.
Semenchenko IIu, Sharafetdinov KhKh, Plotnikova OA, Alekseeva RI,
Sentsova TB, Vorozhko IV. [Markers of immune inflammation in
patients with type 2 diabetes and obesity]. Vopr Pitan.
2013;82:46-50. |
|
|
|
18.
Allen JE. IL-4 and IL-13: Regulators and Effectors of Wound
Repair. Annu Rev Immunol.
2023;41:229-54. |
|
|
|
19.
Burgess JL, Wyant WA, Abdo Abujamra B, Kirsner RS, Jozic I.
Diabetic Wound-Healing Science. Medicina. 2021;
57:1072. |
|
|
|
20.
Holl J, Kowalewski C, Zimek Z, Fiedor P, Kaminski A, Oldak T, et
al. Chronic Diabetic Wounds and Their Treatment with Skin
Substitutes. Cells.
2021;10:655. |
|
|
|
21.
Jin C, Jin Y, Ding Z, Nuch KS, Han M, Shim J, et al. Cellular and
Molecular Mechanisms of Wound Repair: From Biology to Therapeutic
Innovation. Cells. 2025;
14:1850. |
|
|
|